Objectives

1. For students to acquire fundamental knowledge of biophysics, both theoretical and practical, which will serve as a basis for the study of other modules on the Biotechnology degree programme.

2. To familiarise students with the basic mathematical concepts used in physics.

3. To understand the characteristics and properties of motion.

4. To understand the properties and interactions of different types of fluids.

5. To learn the fundamental principles of thermodynamics.

6. To understand the properties and characteristics of waves and radiation.

7. To understand the basic concepts and applications of electromagnetism and electricity.

8. To deepen one’s understanding of radioactivity and its implications for human beings.

9. To understand transport phenomena in biological systems.

Competencies

BASIC COMPETENCIES

CB1: Students have demonstrated that they possess and understand knowledge in a field of study building on the foundations of general secondary education; this is typically at a level which, whilst drawing on advanced textbooks, also includes some aspects requiring knowledge from the cutting edge of their field of study.

CB2: Students should be able to apply their knowledge to their work or profession in a professional manner and possess the skills typically demonstrated through the formulation and defence of arguments and the resolution of problems within their field of study.

CB3: Students should be able to gather and interpret relevant data (usually within their field of study) in order to form judgements that include reflection on relevant social, scientific or ethical issues.

CB4: Students should be able to communicate information, ideas, problems and solutions to both specialist and non-specialist audiences.

CB5: Students should have developed the learning skills necessary to undertake further study with a high degree of autonomy.

GENERAL COMPETENCIES

CG1 – To think in an integrated manner, reason critically and approach problems from different perspectives.

CG2 – Be able to obtain, process, interpret, analyse and synthesise relevant information and results, and draw conclusions on topics related to biotechnology.

CG4 – Interpret experimental results and identify consistent and inconsistent findings.

GC5 – Apply the theoretical and practical knowledge acquired to problem-solving and seek solutions effectively and creatively in both professional and academic contexts.

CG6 – Study and learn independently, organising and planning one’s work, and develop the ability to work in a team and build self-confidence.

SPECIFIC COMPETENCIES:

CE1. – To know and understand the basic concepts of Mathematics, Physics, Chemistry and Biology, as well as the main tools used in these disciplines for the research and development of biotechnological processes.

CE6. – Be able to apply the essential mathematical, statistical and computational methods required for the study, interpretation and control of biotechnological experiments or processes.

Learning outcomes

- Be able to apply basic knowledge of Physics to Biotechnology.

- Solve problems relating to electric fields and understand their relationship with biological systems and measurement systems.

- Practical applications of fluid statics and dynamics.

- Apply the basic concepts and laws of fluid mechanics to the study of biological fluids.

-Apply basic knowledge relating to the concept of a field: gravitational, electric and magnetic fields, as well as the associated forces and potentials.

-Identify the electrical properties of material media and their application to the study of biological phenomena.

- Analyse the response of matter to electromagnetic fields and their spectroscopic applications.

-Identify radioactive decay processes and their biological applications.

-Carry out simple experiments on the phenomena covered in the course content: handling the appropriate equipment, analysing data and results.

Description of the course content

INTRODUCTION

TOPIC 1. THE LANGUAGE OF PHYSICS:

Orders of magnitude and scales. Units and systems of measurement. Scalar and vector quantities. Vectors.

TOPIC 2. MECHANICS:

KINEMATICS: MRU, MRUA, MC and MAS.

DYNAMICS: Forces and Newton’s laws. Linear and angular momentum of a force. Impulse. Work and energy. Conservation laws.

TOPIC 3. FLUID PHYSICS:

HYDROSTATICS: Hydrostatic, atmospheric and manometric pressure. Fundamental principle of hydrostatics. Pascal’s principle. Archimedes’ principle.

HYDRODYNAMICS: Laminar and turbulent flow. Volume flow. Law of Continuity. Bernoulli’s Theorem. Biological membranes and osmotic pressure.

TOPIC 4. THERMODYNAMICS:

States of matter. Properties of solids, liquids and gases. Conduction, convection and radiation. Zeroth Law. Temperature and temperature scales. First Law of Thermodynamics. Thermodynamic processes. Potentials. Internal energy and enthalpy. Heat and Thermal Energy. Work and Physical Energy. Heating, cooling and changes of state. Heat capacity, specific heat and latent heat. Second Law of Thermodynamics. Entropy. Third Law of Thermodynamics. Absolute Zero.

TOPIC 5. FIELDS AND WAVES:

Mechanical and electromagnetic waves. Acoustics and optics. Oscillations. Kinematics and dynamics of a rigid body. Coupling of rigid bodies. Resonance.

TOPIC 6. ELECTROMAGNETIC FIELDS:

ELECTROSTATICS AND MAGNETISM: Electric charges and field lines. Potential, field and Coulomb’s force. Magnetism. Magnetic dipoles and induction.

ELECTRICITY: Active and passive circuit components. Resistors, capacitors, inductors. RC and RLC circuits. Optoelectronics.

TOPIC 7. BIOPHYSICS OF RADIATION: Quantum physics. Wave-particle duality. Radiation-matter interaction. Spectroscopy. Natural and artificial radioactivity. Effects of radioactivity and protection against it.

TOPIC 8. TRANSPORT PHENOMENA: Transport across membranes. Transport of matter. Fick’s laws. Heat transport. Electrical transport. Nerve cells and potentials.

Learning activities

Lecture/Sessions (SESSION in the timetable)

Laboratories (LB on the timetable)

Seminars/Assignments (TRAB in the timetable)

Tutorials/Consultations/Supplementary material for lectures (CN in the timetable)

Assessment (EV on the timetable)

Self-study

Assessment system and criteria

Without prejudice to any other requirements that may be specified in the relevant course syllabus, as a general rule, failure to attend more than 70 per cent of the course’s teaching activities—which require the student’s physical or virtual presence—will result in the loss of the right to continuous assessment during the standard examination period. In this case, the examination to be held during the official period set by the University will be the sole assessment criterion, with the weighting specified in the course syllabus.

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1. TYPES OF CLASSES:

1.1. Theory and exercises will be covered in the lecture sessions and interactive sessions (SESION).

1.2 We will work in teams during the ‘Assignments’ (TRAB) classes.

1.3 We will carry out LB practicals to apply our theoretical knowledge in the Physics laboratory (LB).

2. COURSE ASSESSMENT:

2.1 The module is passed with a FINAL GRADE of 5 or above, calculated as the weighted average of the marks in section 2.2:

0–4.99. Fail

5–6.99. Pass

7–8.99. Good

9–9.99. Distinction

10. First Class

2.2 The module may be passed during the academic year either through continuous assessment or the final examination.

2.2.1 CONTINUOUS ASSESSMENT:

The final mark for the course is the result of several components:

EXAMS: Sessions (30% first mid-term + 30% second mid-term) + Practical sessions (20%)

SELF-ASSESSMENTS and APPLIED ASSIGNMENTS: discussions and theoretical/practical presentations (assignments): 15%

PARTICIPATION, DISCUSSION AND PROPOSALS: 5%

2.2.2 SINGLE FINAL EXAM:

If a student does NOT keep up with the course regularly, or fails to pass the mid-term exams, they must sit the Single Final Exam.

-Date: The final exam will take place on the dates published by the university, for both the ordinary and supplementary examination sessions, which can be found in your exam timetable.

-Format: The exam format will be similar to that of the mid-term exams (see below).

-Content: The entire course syllabus.

3. Type of exam.

-Exams will be held in person using a single digital device, in accordance with university regulations.

-The exam will consist of two parts, both multiple-choice: one on theory and the other on solving numerical exercises.

--THEORY: 10 multiple-choice questions on THEORY or APPLIED THEORY (3 marks), with several answer options, of which ONLY ONE is CORRECT (+1 mark/10 marks) and incorrect answers will result in a deduction of one third of a mark (-0.33 marks).

--PROBLEMS: 3 numerical problems (10 marks), similar to those solved in the session classes.

These are presented as a test in the same format as the theory questions; the numerical exercises must be worked out explicitly in writing on the paper provided. If the exercise is not worked out, it will not be marked favourably, even if the answer marked on the answer sheet is correct.

Timetable

Click on this link to view the detailed timetable in Excel

Bibliography

Essential:

1. Sears, Francis W.

University Physics

6th ed.: Addison Wesley. 1988.

ISBN: 0201640139

2. Villar, R., López, C., Cussó, F.

Physical Fundamentals of Biological Processes

Club Universitario. 2012.

ISBN: 9788415941385

Objectives

1. To understand and explain the main structural characteristics of biomolecules.

2. To understand and be able to carry out the basic experimental techniques used in a biochemistry laboratory.

3. To practise, under supervision, techniques for isolating and purifying proteins.

4. To practise, under supervision, techniques for isolating and purifying nucleic acids.

Competencies

BASIC COMPETENCIES:

CB1 – Students have demonstrated that they possess and understand knowledge in an area of study that builds on the foundations of general secondary education, and is typically at a level which, whilst drawing on advanced textbooks, also includes

certain aspects involving knowledge from the cutting edge of their field of study.

CB2 – Students should be able to apply their knowledge to their work or profession in a professional manner and possess the

skills typically demonstrated through the development and defence of arguments and the resolution of problems within their field of study.

CB3 – Students should have the ability to gather and interpret relevant data (usually within their field of study)

in order to make judgements that include reflection on relevant social, scientific or ethical issues.

CB4 – Students should be able to communicate information, ideas, problems and solutions to both specialist and non-specialist

specialist audiences.

CB5 – Students should have developed the learning skills necessary to undertake further study

with a high degree of autonomy.

GENERAL COMPETENCIES:

CG1 - To think in an integrated manner, reason critically and approach problems from different perspectives.

CG2 – Be able to obtain, process, interpret, analyse and synthesise relevant information and results, and draw conclusions on topics related to biotechnology.

CG3 – Use information in a foreign language

CG4 – Interpret experimental results and identify consistent and inconsistent elements.

CG5 - Apply the theoretical and practical knowledge acquired to problem-solving and seek solutions effectively and creatively in both professional and academic contexts.

CG6 - Study and learn independently, organising and planning one’s work, and develop the ability to work in a team and build self-confidence.

SPECIFIC COMPETENCIES:

CE2 - Work appropriately in a laboratory by applying the basic principles of safety, handling and waste disposal, and by keeping a detailed record of activities.

CE12 – Identify the types of biomolecules and relate their structure to their function, as well as understand metabolic pathways and their regulatory mechanisms, enzyme kinetics and mechanisms of action.

Learning outcomes

Become familiar with the use of the main equipment and consumables commonly found in a biochemistry laboratory

· Identify the fundamental organic functional groups that characterise different biomolecules.

· Interpret the results obtained from basic structural studies of proteins and nucleic acids.

· Retrieve protein and nucleic acid structures from structural databases and use appropriate software to visualise and understand the structure-function relationships of macromolecules.

· Identify conserved motifs and domains in proteins.

· Interpret the relationship between the structure and function of biological membranes, identify transport mechanisms and describe their properties at the molecular level.

Course content

1. MOLECULAR BASICS

2. CARBOHYDRATES

3. LIPIDS

4. NUCLEOTIDES AND NUCLEIC ACIDS

5. AMINO ACIDS AND PROTEINS

Training activities

Lecture/Sessions (SESSION in the timetable)

Laboratory sessions (LB on the timetable)

Seminars/Assignments (TRAB on the timetable)

Tutorials/Consultations/Lecture supplements (CN in the timetable)

Assessment

Independent study

Assessment system and criteria

Without prejudice to any other requirements that may be specified in the relevant course syllabus, as a general rule, failure to attend more than 70 per cent of the course’s teaching activities—which require the student’s physical or virtual presence—will result in the loss of the right to continuous assessment during the standard examination period. In this case, the examination to be held during the official period set by the University will be the sole assessment criterion, with the weighting specified in the course syllabus.

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SUMMARY OF THE ASSESSMENT BY COURSE COMPONENTS

1. THEORY exams (SESSION and ASSIGNMENT): 60% of the mark.

2. LABORATORY PRACTICALS (LB): 30% of the mark.

3. CONTINUOUS ASSESSMENT (SESSION, ASSIGNMENT and LAB): 10% of the mark for each part of the module (THEORY and LABORATORY).

Theory and laboratory tests and examinations, as well as attendance at laboratory sessions, are COMPULSORY.

Failure to sit these tests and examinations or absence from laboratory sessions will result in a fail for the module.

ASSESSMENT OF THEORETICAL CONTENT

1. During the academic year, there will be two eliminatory mid-term exams.

2. The dates, times and lecture theatres for the mid-term exams will be announced via a notice and on the course’s online platform.

3. The exams will consist of 20 multiple-choice questions with four options, only one of which is correct (incorrect answers will result in a 33% deduction from the mark for that question), and will also include essay-type questions similar to those in the TRAB exercises, which will be completed on paper.

4. A pass is achieved with a mark of 5 out of 10.

5. The theory mark will be the average of the two mid-term exams, provided that the mark for both mid-term exams is at least 3 out of 10.

6. If the average mark for the mid-term exams is below 5, if any mid-term exam has a mark below 3, or if a student is marked ‘NP’ (did not sit the exam), they will have to retake the failed mid-term exam(s) in the Ordinary Examination Period (January).

7. If, following the Ordinary Examination Period (January), the mark is still below 5, the student will be required to retake the failed mid-term exam(s) during the Extraordinary Examination Period (May/June).

ASSESSMENT OF PRACTICAL CONTENT

1. The laboratory practicals consist of FIVE SESSIONS. During four sessions, students will receive a theoretical explanation and practise various laboratory techniques; in the fifth session, queries will be addressed and an exam will be held on the techniques and concepts covered.

2. The exam will consist of multiple-choice and/or short-answer questions. Multiple-choice questions will have four options (incorrect answers will result in a deduction of 33 per cent of the question’s mark). A pass is achieved with a mark of 5 out of 10.

3. Attendance at and sitting of the laboratory examinations IS COMPULSORY FOR ALL STUDENTS. Each instance of unexcused absence during the practical sessions will result in a deduction of 25 per cent from the laboratory mark.

4. Failure to attend the practical sessions will result in a fail for the laboratory module and the course.

5. Students who have attended the practical sessions but have not passed the exam must retake the laboratory multiple-choice exam during the Ordinary Examination Period.

6. Failing the Ordinary Examination Session means that students must retake the laboratory multiple-choice exam in the Supplementary Examination Session.

CONTINUOUS ASSESSMENT (CA)

Regarding the CONTINUOUS ASSESSMENT for THEORY:

This will consist of an online test for each topic comprising 10 multiple-choice questions with four or five options, of which only one is correct. Incorrect answers do not result in marks being deducted. Each correctly answered question is worth 1 mark.

Regarding LABORATORY continuous assessment:

This will consist of completing an online self-assessment exercise for each practical session.

Timetable

Click on this link to view the detailed timetable in Excel

Bibliography

Core:

1. Feduchi Canosa E, Romero Magdalena C, Yáñez Conde E, García-Hoz Jiménez C.

Biochemistry. Essential Concepts.

3rd ed. Médica Panamericana. 2025.

ISBN: 9788491106807

Supplementary:

2.- Lehninger AL, Nelson DL, Cox MM and Cuchillo Foix CM.

Lehninger. Principles of Biochemistry

7th ed. Omega. 2018.

ISBN: 9788428216678

Other:

3.- John W. Baynes; Marek H. Dominiczak

Medical Biochemistry

Elsevier. 2024.

ISBN: 978-841382582

4. Meisenberg, Simmons

Principles of Medical Biochemistry

4th ed. Elsevier. 2018.

ISBN: 9788491132974

Objectives

• To be able to identify animal and plant cells and their organelles.

• Understand the structure and function of cellular organelles.

• Identify the structure and function of the plasma membrane and cellular transport mechanisms.

• Understand the relationships between cells and their environment.

• Understand the basic concepts of DNA structure and organisation, as well as its replication, transcription and translation mechanisms.

Competencies

CORE COMPETENCES

CB1: Students should have demonstrated that they possess and understand knowledge in an area of study building on the foundations of general secondary education; this is typically at a level which, whilst drawing on advanced textbooks, also includes some aspects requiring knowledge from the cutting edge of their field of study. 

CB2: Students should be able to apply their knowledge to their work or vocation in a professional manner and possess the skills typically demonstrated through the development and defence of arguments and the resolution of problems within their field of study. 

CB3: Students should be able to gather and interpret relevant data (usually within their field of study) in order to form judgements that include reflection on relevant social, scientific or ethical issues. 

CB4: Students should be able to communicate information, ideas, problems and solutions to both specialist and non-specialist audiences. 

CB5: Students should have developed the learning skills necessary to undertake further study with a high degree of autonomy.

GENERAL COMPETENCES

CG1 – Ability to think in an integrated manner, to reason critically and to approach problems from different perspectives. /GC1 – Ability to think in a multi-level way, to develop critical questioning and to tackle problems from different perspectives. 

CG2 – Ability to gather, process, interpret, analyse and synthesise relevant information and results, and draw conclusions on topics

related to biotechnology. / Being able to gather, process, interpret, analyse and synthesise relevant information and results,

as well as to draw conclusions on issues relating to biotechnology.

CG3 - The ability to use international information sources and to communicate in a second language of

international relevance./ Ability to access and use international information sources and to communicate in a relevant

foreign language.

CG4 – Interpreting experimental results and identifying consistent and inconsistent elements./ Capacity to interpret

experimental results and to identify consistent and inconsistent elements.

CG5 - Apply the theoretical and practical knowledge acquired to problem-solving and seek solutions in an

effective and creative manner in both professional and academic contexts. / Capacity to apply the acquired theoretical and practical

knowledge to problems, and to find effective and creative solutions in both professional and academic contexts.

CG6 – Ability to assimilate new concepts and learn independently, whilst organising and planning one’s work, and

develop the ability to work in a team and build self-confidence. / Capability to assimilate new concepts and learn independently, to

organise and plan their own work, and to become a self-confident team player.

SPECIFIC COMPETENCIES

CE1 – To know and understand the basic concepts of Mathematics, Physics, Chemistry and Biology, as well as the main

tools used in these disciplines for research and development in biotechnology processes./ To learn and understand

the basic concepts of Mathematics, Physics, Chemistry and Biology, as well as the main tools used in these disciplines for the research

and development of biotechnological processes.

CE2 - The ability to work appropriately in a laboratory, applying the basic principles of safety, handling and

waste disposal, whilst maintaining a detailed record of activities./ Being able to work in a laboratory in a proper manner, i.e.,

applying the basic principles of handling and waste disposal, safety, whilst always keeping a record of activities.

CE9 – Understanding the structure and function of the cell, including both metabolism and gene expression, and describing the

molecular mechanisms of transport and signal transduction./ To understand the structure and function of the cell, covering both its metabolism

and gene expression; to describe the molecular mechanisms of transport and signal transduction.

Learning outcomes

• To be able to identify animal and plant cells and their organelles.

• To understand the structure and function of cellular organelles.

• To identify the structure and function of the plasma membrane and the mechanisms of cellular transport.

• To understand the relationships between cells and the environment.

• To understand the basics of the structure and organisation of DNA and its mechanisms of replication, transcription and translation.

Course description

PROGRAMME: INTRODUCTION TO CELL BIOLOGY.

Chapter 1. The cell. Prokaryotic and eukaryotic cells.

Chapter 2. Membrane structure.

Chapter 3. Membrane Transport.

Chapter 4. Electrical Properties of Membranes.

Chapter 5. The cytoskeleton. Intermediate filaments.

Chapter 6. The Cytoskeleton. Microtubules.

Chapter 7. The Cytoskeleton. Microfilaments.

Chapter 8. The Nucleus.

Chapter 9. Intracellular Compartments and Protein Sorting.

Chapter 10. Intracellular Membrane Transport.

Chapter 11. Mitochondria and Chloroplasts.

Learning activities

Lectures/Sessions (SESSION in the timetable)

Laboratory sessions (LB on the timetable)

Seminars/Assignments (TRAB on the timetable)

Tutorials/Consultations/Lecture supplements (CN in the timetable)

Assessment (EV on the timetable)

Self-study

Assessment system and criteria

Without prejudice to the possibility of establishing another requirement in the relevant course syllabus, as a general rule, failure to attend more than 70 per cent of the course’s learning activities that require the student’s physical or virtual presence will result in the loss of the right to continuous assessment in the ordinary examination session. In this case, the examination to be held during the official period set by the University will be the sole assessment criterion, with the weighting assigned to it in accordance with the course syllabus.

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CONTINUOUS ASSESSMENT

• Two compulsory tests, one halfway through the semester and the other at the end. This component accounts for 65% of the final mark. A minimum mark of 4.5 is required to pass the exams in all examination sessions

• Completion of assignments, attitude and attendance: 15 per cent of the final mark.

• Laboratory sessions: 20 per cent of the final mark.

o Laboratory sessions take place on consecutive days, totalling 15 hours. Attendance is compulsory.

o A test will be set at the end of the laboratory sessions. A minimum mark of 4.5 is required to pass the test.

REGULAR EXAMINATION PERIOD

• Exam during the ordinary examination period covering the parts of the course not assessed via tests, and the content of the laboratory sessions, should the exam not have been passed during the practical sessions. This takes place at the end of the semester. A minimum mark of 4.5 in each part is required to pass the exams.

SUPPLEMENTARY EXAM

• Exam held during the supplementary examination period for those parts of the course not passed via tests, and for the content of the laboratory practicals, should the exam not have been passed during the practical period. This takes place at the end of the academic year. A minimum mark of 4.5 in each part is required to pass the exams.

Timetable

Click on this link to view the detailed timetable in Excel

Bibliography

Essential:

1. Alberts et al.

Molecular Biology of the Cell

6th ed. Garland Science. 2014.

ISBN: 9780815344322

Supplementary:

2.- Alberts et al.

Introduction to Cell Biology

5th ed. Panamericana. 2021.

ISBN: 9786078546442

Objectives

The aim of this module is to provide the necessary mathematical foundations for a graduate in Biotechnology, so that they can apply these as an essential tool in technological developments and scientific models relating to biotechnological processes. It aims to help students master the mathematics required to understand other subjects in the fields of physics, chemistry and biology.

Competencies

BASIC COMPETENCIES

CB1: Students should have demonstrated that they possess and understand knowledge in an area of study building on the foundations of general secondary education; this is typically at a level which, whilst drawing on advanced textbooks, also includes certain aspects requiring knowledge from the cutting edge of their field of study. 

CB2: Students should be able to apply their knowledge to their work or profession in a professional manner and possess the competences typically demonstrated through the development and defence of arguments and the resolution of problems within their field of study. 

CB3: Students should be able to gather and interpret relevant data (usually within their field of study) in order to form judgements that include reflection on relevant social, scientific or ethical issues. 

CB4: Students should be able to communicate information, ideas, problems and solutions to both specialist and non-specialist audiences. 

CB5: Students should have developed the learning skills necessary to undertake further study with a high degree of autonomy. 

GENERAL COMPETENCIES

CG1 – To think in an integrated manner, reason critically and approach problems from different perspectives.

CG2 – Be able to obtain, process, interpret, analyse and synthesise relevant information and results, and draw conclusions on topics related to biotechnology.

CG4 – Interpret experimental results and identify consistent and inconsistent findings.

GC5 – Apply the theoretical and practical knowledge acquired to problem-solving and seek solutions effectively and creatively in both professional and academic contexts.

CG6 – Study and learn independently, organising and planning one’s work, and develop the ability to work in a team and build self-confidence.

SPECIFIC COMPETENCIES

CE1. – To know and understand the basic concepts of Mathematics, Physics, Chemistry and Biology, as well as the main tools used in these disciplines for research and the development of biotechnological processes.

Learning Outcomes

- To understand mathematics as an essential tool for the development of scientific and technological knowledge.

- Formulate and solve problems using the language of mathematics.

- Identify mathematical models of relevance to biotechnology.

Course content

1. DIFFERENTIAL CALCULUS

Revision of elementary real functions. Derivative of a real function of a real variable. Rules of differentiation. Higher-order derivatives. Taylor’s polynomial. Derivative of a real function of several real variables. Partial derivatives. Applications of differential calculus.

2. INTEGRAL CALCULUS

Concept of the indefinite integral and its properties. Calculation of antiderivatives of a real function of a real variable: methods of integration. The definite integral: the fundamental theorem of calculus. Barrow’s rule. Concept of the multiple integral. Integration of functions of several variables. Applications of integral calculus.

3. DIFFERENTIAL EQUATIONS

The concept of a differential equation and its solution. Ordinary differential equations. Integration of differential equations. Applications of ordinary differential equations.

4. LINEAR ALGEBRA

Types of matrices and operations on matrices. Calculation of determinants of square matrices. Rank and inverse of a matrix. Systems of linear equations and their matrix representation. Rouché–Frobenius theorem. Cramer’s rule. Gauss’s method for solving systems of equations. Applications of linear algebra.

Learning activities

Lecture/Sessions (SESSION in the timetable)

Laboratories (LB in the timetable)

Seminars/Assignments (TRAB in the timetable)

Tutorials/Consultations/Complements to lectures (CN in the timetable)

Assessment (EV on the timetable)

Self-study

Assessment system and criteria

Without prejudice to any other requirements that may be specified in the relevant course syllabus, as a general rule, failure to attend more than 70 per cent of the course’s teaching activities—which require the student’s physical or virtual presence—will result in the loss of the right to continuous assessment during the standard examination period. In this case, the examination to be held during the official period set by the University will be the sole assessment criterion, with the weighting specified in the course syllabus.

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The assessment process will consist of verifying and evaluating the student’s acquisition of the learning outcomes. To this end, the following assessment activities will be used to determine the extent to which each of the listed learning outcomes has been mastered, and these will consist of:

- Final face-to-face assessment tests, consisting of written examinations covering the content covered in the teaching activities.

-Face-to-face assessment tests designed to put into practice the concepts studied in the module, consisting of problem-solving and the preparation and presentation of projects based on case studies.

- Activities submitted by students via the virtual classroom (assignments, set exercises), as well as in-class presentations.

The results obtained by the student in the module will be graded according to the following numerical scale from 0 to 10, expressed to one decimal place, to which the corresponding qualitative grade may be added:

a. 0–4.9: Fail (SS).

b. 5.0–6.9: Pass (AP).

c. 7.0–8.9: Good (NT).

d. 9.0–10: Distinction (SB).

The distinction ‘Honours’ shall be awarded to students who have obtained a mark of 9.0 or higher. The number of students awarded this distinction may not exceed five per cent of those enrolled on the course in the relevant academic year, unless the number of enrolled students is fewer than 20, in which case only one ‘First Class Honours’ may be awarded.

The course is divided into two parts: Part 1 covers Differential Calculus and Integral Calculus; Part 2 covers Differential Equations and Linear Algebra. Throughout the four-month term, there will be two mid-term examinations, one for each part, in which students’ competencies will be assessed in a manner that reflects the learning activities undertaken. In addition, a series of assignments and activities covering both parts will be set for completion both inside and outside the classroom.

The criteria for continuous assessment are as follows:

• Mid-term Exam 1 is the first mid-term exam for the module. (34%). Covers Part 1 on Differential and Integral Calculus.

• Mid-term Exam 2: this is the second mid-term exam for the module. (34%). Covers Part 2, relating to Differential Equations and Linear Algebra.

• Online assignment submissions (15%). Covering Part 1 and Part 2.

• Practical assignments and presentations (17 per cent). Covering Part 1 and Part 2.

The final continuous assessment mark is calculated using the marks from the two mid-term exams, which account for 68 per cent (34 per cent each), and the marks from the remaining activities, which account for 32 per cent (15 per cent for online assignments and 17 per cent for practical work).

Students may PASS THROUGH CONTINUOUS ASSESSMENT if they achieve a mark of 5 out of 10 or higher when the percentages indicated are applied, i.e. taking into account the weighted scores of the various assessments listed above. However, this is subject to achieving a minimum mark of 4 out of 10 in both mid-term exams; otherwise, students cannot pass via continuous assessment. The final course mark based on continuous assessment will be published before the official exam date for the ordinary examination session.

Students who do not pass the module through continuous assessment may sit the exam in the ordinary examination session.

FEBRUARY REGULAR EXAM SESSION:

This consists of an exam which assesses students’ competencies in line with the learning activities undertaken. It comprises two parts, corresponding to each of the two mid-term exams: Part 1 corresponds to the first mid-term exam, and Part 2 corresponds to the second mid-term exam. These two parts will be marked separately.

Students may choose to sit the entire exam or just one of the two parts if they wish to retain the mark obtained in the other part (in this case, they will be examined only on mid-term exam 1 or mid-term exam 2). Only students who have achieved a mark of 4.0 or higher in either the first or second mid-term exam may be exempted from that part and not sit it in the ordinary examination session. To pass the module, the overall average mark must be 5.0 or higher.

If students choose to sit the exam for the full module, in order to pass the module the total exam mark must be 5.0 or above, and the mark recorded on their academic transcript will be that obtained in that exam, as marks from continuous assessment will not be taken into account.

Under no circumstances will any part of the course be exempted or carried over from the ordinary examination session to the extraordinary session. Therefore, students who have not passed the course in the ordinary session will have the entire course outstanding and may sit the extraordinary session.

JULY EXTRAORDINARY EXAMINATION SESSION:

A single examination will be held covering the full syllabus of the module, without two separate parts, in which the learning outcomes will be assessed in a way that reflects the learning activities undertaken. The final mark will be that obtained in this exam (accounting for 100% of the mark), and this mark will be recorded in the academic transcripts. To pass the module, the mark in the supplementary exam must be 5.0 or above.

Timetable

Click on this link to view the detailed timetable in Excel

Bibliography

Core:

1. Guervos Sánchez, Esther

Fundamentals of Mathematics: Theoretical Concepts and Problems

Bellisco. 2005.

ISBN: 8496486141

2. Guervós Sánchez, Esther

Introduction to Calculus

García-Maroto Editores. 2008.

ISBN: 9788493629984

Supplementary:

3.- Guevós, E; García, M.B.; González, A.

Applied Mathematics

García-Moroto Editores. 2008.

ISBN: 9788493629991

4.- Nakos, George

Linear Algebra with Applications

Madrid: Thomson, 1999. 1999.

ISBN: 9687529865

5. Pedro de Mingo

Calculus

Madrid: Bellisco. 2006.

ISBN: 8448117700

Objectives

Biotechnology is based on the production of chemical compounds through technological processes that utilise living organisms. It requires a sound grasp of basic biological and chemical knowledge to enable students to understand these processes.

The main objective of this module is to introduce students to the world of chemistry for application in their professional practice. To this end, students will be taught to:

Understand the basic principles of chemistry.

Be able to apply this knowledge to solving practical problems.

Develop practical laboratory skills.

Work as part of a team and achieve a shared outcome by putting the theoretical concepts learnt into practice.

Competencies

BASIC COMPETENCIES

CB1: Students have demonstrated that they possess and understand knowledge in a field of study building on the foundations of general secondary education, typically at a level which, whilst drawing on advanced textbooks, also includes some aspects requiring knowledge from the cutting edge of their field of study.

CB2: Students should be able to apply their knowledge to their work or profession in a professional manner and possess the skills typically demonstrated through the development and defence of arguments and the resolution of problems within their field of study.

CB3: Students should be able to gather and interpret relevant data (usually within their field of study) in order to form judgements that include reflection on relevant social, scientific or ethical issues.

CB4: Students should be able to communicate information, ideas, problems and solutions to both specialist and non-specialist audiences.

CB5: Students should have developed the learning skills necessary to undertake further study with a high degree of autonomy.

GENERAL COMPETENCIES

CG1 – To think in an integrated manner, reason critically and approach problems from different perspectives.

CG2 – Be able to obtain, process, interpret, analyse and synthesise relevant information and results, and draw conclusions on topics related to biotechnology.

CG4 – Interpret experimental results and identify consistent and inconsistent findings.

GC5 – Apply the theoretical and practical knowledge acquired to problem-solving and seek solutions effectively and creatively in both professional and academic contexts.

CG6 – Study and learn independently, organising and planning one’s work, and develop the ability to work in a team and build self-confidence.

SPECIFIC COMPETENCIES

CE1. – To know and understand the basic concepts of Mathematics, Physics, Chemistry and Biology, as well as the main tools used in these disciplines for the research and development of biotechnological processes.

CE2. – Work appropriately in a laboratory, applying the basic principles of safety, handling and waste disposal, and keeping a detailed record of activities.

Learning Outcomes

- To understand the composition of matter and its physical and chemical changes.

- Recognise the types of bonds in a chemical compound and the reactivity based on them.

-To use chemical nomenclature and representation accurately, and to understand the concept of the mole and stoichiometry in chemical processes.

-Understand basic concepts relating to solutions and chemical equilibria.

-Describe and analyse the chemical principles applicable to biotechnology.

-Demonstrate skill and proficiency in an experimental laboratory, including the use of scientific equipment.

-Know how to handle chemicals and assess the risks associated with their use in the laboratory.

- Produce reports on the practical work carried out in the various laboratories.

-Apply theoretical knowledge to practice: problem-solving.

Course content

Topic 1: The composition of matter.

1.1 Classification of matter: Pure substances and mixtures. Methods of

separation. Extensive and intensive properties.

1.2 Chemical elements. Atomic number. Mass number.

Atomic mass.

1.3 Chemical compounds. Atoms, molecules and ions.

1.4. Periodic table. Periodic properties of the elements: Atomic radius

, ionisation energy, electron affinity, electronegativity.

1.5 Moles and molar mass. Empirical and molecular formulae.

Topic 2. Nomenclature in Inorganic Chemistry.

Topic 3. – Chemical bonding

3.1 Ionic bonding.

3.2 Covalent Bond. Lewis Structures. Dipole Moment. Molecular Geometry

. Orbital theory. Molecular orbitals. Hybridisation.

3.3 Metallic Bonding.

Topic 4. – Liquid and solid states. Changes of state.

4.1 Intermolecular forces.

4.2 Amorphous and crystalline solids. Types of crystals.

4.3 Liquid–vapour equilibrium

4.3.1 Vapour pressure. Boiling point.

4.3.2 Liquefaction of gases. Critical point

4.4 Solid–liquid equilibrium: melting point

4.5 Solid–vapour equilibrium: sublimation.

4.6 Phase diagrams. Triple point.

Topic 5. Solutions.

5.1 Types of solutions. Measures of concentration.

5.2 Stoichiometry of chemical reactions in solution.

5.3 Saturation and solubility.

5.4 Factors affecting solubility:

5.5 Colligative properties of solutions. Ideal solutions. van’t Hoff factor

van’t Hoff factor.

Topic 6 – Chemical reactions. Stoichiometry.

6.1 Chemical equations.

6.2 Types of chemical reactions:

6.2.1 Acid-base reactions.

6.2.2 Precipitation reactions.

6.2.3 Redox reactions. Balancing redox reactions.

6.3 Stoichiometric calculations based on chemical equations.

6.4 Limiting reactant. Reaction yield.

Topic 7. Chemical equilibrium.

7.1 Reactions at equilibrium.

7.2 Equilibrium constant. Homogeneous equilibrium. Heterogeneous equilibrium.

7.3 Equilibrium calculations.

7.4 Factors affecting chemical equilibrium. Le Chatelier’s principle.

7.5 Free energy and chemical equilibrium.

Topic 8. Acid-base equilibria.

8.1 Definitions of acids and bases.

8.2 Ionisation constant. Strength of acids and bases.

8.3 Autoionisation of water. pH scale.

8.4 Calculating the pH of acid and base solutions. Polyprotic acids.

8.5 Calculating the pH of salt solutions. Acidic and basic ions.

8.6 Mixed solutions: the common-ion effect. Buffers.

Topic 9. Electrochemistry.

9.1 Electrochemical cells. Types of cells.

9.2 Cell potential. Standard electrode potential. Spontaneity of

redox reactions.

9.3 Dependence of cell potential on concentration. The

Nernst equation. Concentration cells.

9.4 Electrolytic cells. Faraday’s law

Learning activities

Lecture/Sessions (SESSION in the timetable)

Laboratory sessions (LB in the timetable)

Seminars/Assignments (TRAB on the timetable)

Tutorials/Consultations/Lecture supplements (CN in the timetable)

Assessment (EV on the timetable)

Self-study

Assessment system and criteria

Without prejudice to any other requirements that may be specified in the relevant course syllabus, as a general rule, failure to attend more than 70 per cent of the course’s teaching activities—which require the student’s physical or virtual presence—will result in the loss of the right to continuous assessment during the standard examination period. In this case, the examination to be held during the official period set by the University will be the sole assessment criterion, with the weighting specified in the course syllabus.

----

To pass this module, students must:

1. Have completed ALL the laboratory practicals.

2. Achieve a mark of five points or higher by adding together the percentages set out below:

CONTINUOUS ASSESSMENT:

- Inorganic Formulation and Nomenclature exam (10% of the final mark). YOU MUST PASS THIS WITH A MARK OF 5 OR HIGHER.

- Mid-term exam 1: Topics 1 and 3 to 5 (25% of the final mark)

- Mid-term Exam 2: Topics 6 to 9 (25% of the final mark)

These three assessments will count towards the final mark provided a mark of 5 or above is achieved.

The two mid-term exams can be offset if a mark of 4 or above is achieved. If a student fails or is unable to offset the marks, they must sit the exam for the failed part(s) during the ordinary and/or supplementary examination sessions.

- Laboratory practicals: 20% + 5%. ATTENDANCE AT THE PRACTICALS IS COMPULSORY

* Practical work will be assessed via a final exam (20%). Minimum mark required to be included in the average: 4.

* 5 per cent: Completion of laboratory reports and exercises.

- Student work: 15%

* 5% Jove platform test

* 10% Class activities (handing in problems, working at the blackboard, etc.)​

TO QUALIFY FOR CONTINUOUS ASSESSMENT, STUDENTS MUST ACHIEVE A MINIMUM AVERAGE MARK OF 5 POINTS ACROSS THE TWO MID-TERM EXAMS.

The maximum final mark will be 10 marks. To pass the module, the final mark must be 5 marks or higher.

REGULAR EXAM SESSION:

If a student does not meet the requirements for the continuous assessment criteria to apply, they must sit the ordinary examination for any failed components, whether the written assignment, mid-term exam(s) and/or any part of the practical work, with the percentages described above being applied to calculate their final mark. To pass, students must achieve a final mark of 5 out of 10.

EXTRAORDINARY EXAMINATION SESSION:

If a student fails the ordinary assessment, they must sit the extraordinary assessment for those parts in which they have failed – the written assignment, mid-term exam or exams, and/or the part of the practical work in which they have failed – with the percentages described above being applied to calculate their final mark. To pass, students must achieve a final mark of 5 out of 10.

Exam format:

- Mid-term exams: These will consist of a section of short-answer/multiple-choice questions and a section of problems.

- Practical examination: The practicals will be assessed through the preparation of a buffer solution in groups in the laboratory and through an individual examination on the LAST DAY of the practicals. This examination will consist of a test and problems relating to the practicals carried out.

Attendance at practical sessions is compulsory. Students are not permitted to miss any practical sessions unless there is a very valid reason.

Timetable

Click on this link to view the detailed timetable in Excel

Bibliography

Core:

1. Atkins, Jones

Principles of Chemistry

Panamericana. 2012.

ISBN: 9789500602822

2. Chang, Goldsby

Chemistry

McGraw-Hill Interamericana de España S.L. 2017.

ISBN: 9786071513939

3. J. M. TEIJÓN, J. A. GARCÍA, Y. JIMÉNEZ and Y. GUERRERO

Chemistry through Problems

Tebar. 2006.

ISBN: 9788473602266

4. López Cancio, José Antonio

Chemistry Problems

Madrid [etc.]: Prentice-Hall, 2000. 2000.

ISBN: 9788420529950

5. Mahan, Bruce M.

Chemistry: A University Course

Argentina [etc.]: Addison Wesley, 1990. 1990.

ISBN: 0201644193

6. Petrucci, R.

General Chemistry

Pearson. 2017.

ISBN: 9788490355336

Objectives

Students will learn the main techniques of descriptive statistics, how to model the uncertainty associated with random phenomena using probability models, and how to estimate and test hypotheses regarding the parameters of one or more populations.

Competencies

BASIC COMPETENCES

CB1: Students should have demonstrated that they possess and understand knowledge in an area of study building on the foundations of general secondary education; this is typically at a level which, whilst drawing on advanced textbooks, also includes some aspects requiring knowledge from the cutting edge of their field of study. 

CB2: Students should be able to apply their knowledge to their work or profession in a professional manner and possess the skills typically demonstrated through the development and defence of arguments and the resolution of problems within their field of study. 

CB3: Students should be able to gather and interpret relevant data (usually within their field of study) in order to form judgements that include reflection on relevant social, scientific or ethical issues. 

CB4: Students should be able to communicate information, ideas, problems and solutions to both specialist and non-specialist audiences. 

CB5: Students should have developed the learning skills necessary to undertake further study with a high degree of autonomy. 

GENERAL COMPETENCIES

CG1 – To think in an integrated manner, reason critically and approach problems from different perspectives.

CG2 – Be able to obtain, process, interpret, analyse and synthesise relevant information and results, and draw conclusions on topics related to biotechnology.

CG4 – Interpret experimental results and identify consistent and inconsistent elements.

CG5 – Apply the theoretical and practical knowledge acquired to problem-solving and seek solutions effectively and creatively in both professional and academic contexts.

CG6 – Study and learn independently, organising and planning one’s work, and develop the ability to work in a team and build self-confidence.

SPECIFIC COMPETENCIES

CE1. – To know and understand the basic concepts of Mathematics, Physics, Chemistry and Biology, as well as the main tools used in these disciplines for the research and development of biotechnological processes.

CE6. – Be able to apply the essential mathematical, statistical and computational methods required for the study, interpretation and control of biotechnological experiments or processes.

Learning outcomes

Interpret the levels of precision, confidence and error in the conclusions of a statistical study.

Use a statistical software package at user level.

Analyse data descriptively.

Calculate confidence intervals for means and proportions, determining the appropriate sample size.

Understand the relationship between confidence intervals and hypothesis testing.

Interpret the p-value and draw conclusions.

Distinguish between independent and paired samples.

Distinguish between parametric and non-parametric methods.

Compare one or two means or proportions depending on the type and number of data points.

Understand the concepts of risk factor, relative risk and odds ratio

Description of the content

• T1: Descriptive statistics. Types of experiments, types of variables, organisation and coding of data, summarisation of qualitative variables (frequencies, odds ratio, relative risk) and quantitative variables (measures of central tendency, quantiles, dispersion and skewness), graphs of qualitative and quantitative variables.

• T2: Probability. Events, set theory, definitions of probability, Venn diagrams, conditional probability, independence of events, the total probability theorem, Bayes’ theorem.

• T3: Probability distributions. Random variables; binomial, Poisson, uniform and normal distributions; typification; approximations between distributions.

• T4: Statistical inference (I). Sources of error, sampling distribution, central limit theorem, standard error, point estimates and confidence intervals for means and proportions.

• T5: Statistical inference (II). Hypothesis testing, types of error, power, significance level, p-value, one-tailed and two-tailed tests, statistical tests for comparing means and proportions, z (standard normal distribution), Student’s t-test, Fisher–Snedecor, chi-squared, confidence intervals for differences in means and proportions, correlation, parametric and non-parametric tests

Learning activities

Lecture/Sessions (SESSION in the timetable)

Laboratory sessions (LB in the timetable)

Seminars/Assignments (TRAB in the timetable)

Tutorials/Consultations/Lecture supplements (CN in the timetable)

Assessment (EV on the timetable)

Self-study

Assessment system and criteria

Without prejudice to any other requirements that may be specified in the relevant course syllabus, as a general rule, failure to attend more than 70 per cent of the course’s teaching activities—which require the student’s physical or virtual presence—will result in the loss of the right to continuous assessment during the standard examination period. In this case, the examination to be held during the official period set by the University will be the sole assessment criterion, with the weighting specified in the course syllabus.

----

- Assessment of the content covered in the sessions and assignments: This accounts for 60 per cent of the final mark for the module. Two exams will be held throughout the semester; these will be ‘pseudo-exemption’ exams, with a mark of 5 or above required to pass (students cannot attempt the second part without being able to complete the calculations in the first part). The first exam will account for 15 per cent of the final mark and the second for 45 per cent. Should you obtain a mark below 5, you must sit the exam during the ordinary and/or supplementary examination periods.

- Practical assessment: designed to put into practice the concepts studied in each module. This assessment is conducted in person. It accounts for 25 per cent of the final mark for the module.

- Oral presentation in pairs, in which students will explain the mathematical aspects of the design and analysis of a hypothetical experiment (15 per cent).

Timetable

Click on this link to view the detailed timetable in Excel

Bibliography

Essential:

1. Geoffrey R. Norman

Biostatistics: the bare essentials

PMPH-USA Limited. 2014.

ISBN: 1607951789

2. Marc Triola

Biostatistics for the Biological and Health Sciences

Financial Times Prentice Hall. 2017.

ISBN: 9780134039015

Objectives

- To understand the fundamental concepts relating to the nature, organisation, function and transmission of genetic material. To understand the principles of Mendelian inheritance and their implications.

- To acquire knowledge of the structure of genetic material, its transmission and expression in different organisms.

- To identify the sources of genetic variation and the different types of mutations, as well as to understand techniques for genetic analysis and manipulation.

- To acquire knowledge of general aspects of genomes.

- To master the basic scientific terminology of the subject.

- To be familiar with the bibliographic sources related to the subject and how to access them.

- To develop skills and abilities in the field of genetics with a view to future professional practice.

Competencies

BASIC COMPETENCIES

CB1: Students have demonstrated that they possess and understand knowledge in an area of study building on the foundations of general secondary education; this is typically at a level which, whilst drawing on advanced textbooks, also includes some aspects requiring knowledge from the cutting edge of their field of study.

CB2: Students should be able to apply their knowledge to their work or vocation in a professional manner and possess the competencies typically demonstrated through the development and defence of arguments and the resolution of problems within their field of study.

CB3: Students should be able to gather and interpret relevant data (usually within their field of study) in order to form judgements that include reflection on relevant social, scientific or ethical issues.

CB4: Students should be able to communicate information, ideas, problems and solutions to both specialist and non-specialist audiences.

CB5: Students should have developed the learning skills necessary to undertake further study with a high degree of autonomy.

GENERAL COMPETENCIES

CG1 – To think in an integrated manner, reason critically and approach problems from different perspectives.

CG2 – Be able to obtain, process, interpret, analyse and synthesise relevant information and results, and draw conclusions on topics related to biotechnology.

CG3 – Be able to use international sources of information, as well as to communicate in a second language of international relevance.

CG4 – Interpret experimental results and identify consistent and inconsistent elements.

CG5 – Apply the theoretical and practical knowledge acquired to problem-solving and seek solutions effectively and creatively in both professional and academic contexts.

CG6. – Study and learn independently, organising and planning one’s work, and develop the ability to work in a team and build self-confidence.

SPECIFIC COMPETENCIES

CE2. – Work appropriately in a laboratory by applying the basic principles of safety, handling and waste disposal, and by keeping a detailed record of activities.

CE11. – Understand the structure, organisation and regulation of gene expression, as well as the molecular bases of genetic and epigenetic variation.

Learning outcomes

• Understand the importance and use of mutants in genetic analysis.

• Calculate the different possible gametic types – as well as their frequencies – based on a genotype.

• Distinguish between and analyse the different types of Mendelian segregation based on the allelic and/or genetic relationships involved.

• Correctly apply the allelic test and the concept of gene complementation.

• To understand the structure and function of the eukaryotic chromosome.

• Construct genetic maps

• Recognise the different types of chromosomal mutations and their effect on the phenotype.

• Understand the genetic implications of the DNA double helix model.

• Understand the molecular basis of DNA mutation and repair.

• Understand the function and inheritance of additive genes.

Description of the content

TRANSMISSION OF HEREDITARY MATERIAL

TOPIC 1: MENDELIAN GENETICS. Mendel’s experiments. Phenotype and genotype. Mendelian inheritance in humans.

TOPIC 2: EXTENSIONS OF MENDELIAN GENETIC ANALYSIS. Multiple alleles. Modifications of the dominance relationship. Gene interactions. Penetrance and expressivity.

TOPIC 3: CHROMOSOMAL BASES OF INHERITANCE. The chromosomal theory of inheritance. Prokaryotic and eukaryotic chromosomes. Cell division: mitosis and meiosis. Linkage and recombination. Genetic maps.

TOPIC 4: PATTERNS OF INHERITANCE. Pedigrees. The genetic basis of human diseases.

STRUCTURE OF HEREDITARY MATERIAL

TOPIC 5. GENETIC MATERIAL. DNA as genetic material. RNA as genetic material. Composition and structure of nucleic acids. Structure of DNA. Structure of chromosomes.

TOPIC 6. REPLICATION OF HEREDITARY MATERIAL. General characteristics in prokaryotes and eukaryotes.

EXPRESSION AND VARIATION OF GENETIC MATERIAL

TOPIC 7. EXPRESSION OF GENETIC INFORMATION. The gene-enzyme relationship. Transcription. Processing. Translation. The genetic code.

TOPIC 8. REGULATION OF GENE ACTIVITY IN EUKARYOTES. Transcriptional and post-transcriptional regulation. Epigenetics. microRNAs.

TOPIC 9. MUTATION AND GENETIC VARIATION. Molecular basis. Gene mutations. Repair. Mutagenesis. Transposition. Mutation and adaptation.

TOPIC 10. STRUCTURAL AND NUMERICAL CHROMOSOMAL MUTATIONS. Types. Origins. Genetic consequences.

TOPIC 11. IDENTIFICATION OF THE GENETIC BASIS OF DISEASES. Linkage analysis. Association analysis. Direct genome sequencing.

TOPIC 12. CANCER GENETICS. Oncogenes and tumour suppressor genes. Instability

GENETIC ENGINEERING AND GENOMICS

TOPIC 13. GENETIC ANALYSIS AND MANIPULATION. Recombinant DNA technology. Polymerase chain reaction (PCR). Hybridisation. Sequencing. Transgenesis. Gene editing.

TOPIC 14. STRUCTURAL, FUNCTIONAL AND COMPARATIVE GENOMICS. Genome composition. Genomic databases. Transcriptomics.

Teaching activities

Lecture/Sessions (SESSION in the timetable)

Laboratory sessions (LB in the timetable)

Seminars/Assignments (TRAB in the timetable)

Tutorials/Consultations/Lecture supplements (CN in the timetable)

Assessment (EV on the timetable)

Self-study

Assessment system and criteria

Without prejudice to any other requirements that may be specified in the relevant course syllabus, as a general rule, failure to attend more than 70 per cent of the course’s teaching activities—which require the student’s physical or virtual presence—will result in the loss of the right to continuous assessment during the standard examination period. In this case, the examination to be held during the official period set by the University will be the sole assessment criterion, with the weighting specified in the course syllabus.

----

Face-to-face final assessment

Participation in forums and other participatory activities: assessed on the basis of the student’s use of and participation in face-to-face and virtual sessions, workshops, forums, etc.

Practical assessment: designed to put into practice the concepts studied in each module. The assessment of this knowledge takes place at the end of the module in person.

Assignments: this criterion assesses the work students submit via the virtual classroom (assignments, projects, case studies) as well as in-class presentations.

Student assessment will be carried out taking into account not only examinations but also practical work and the submission of assignments throughout the term, in accordance with the following criteria:

1. Having completed the laboratory practicals.

2. Achieving a mark of five points or higher by adding together the percentages set out below:

a) Theory. This accounts for 70% of the final mark.

- Mid-term exam 1: Topics 1 to 6.

- Mid-term exam 2: Topics 7 to 13.

These exams may be averaged provided that a mark of at least 4 is obtained and provided that the average of the two mid-term exams is 5 or above.

If a student fails or is unable to make up for the marks through the mid-term exams, they must sit the examination for the failed module during the ordinary and/or supplementary examination sessions.

b) Laboratory practicals: 20% of the final mark.

c) Student-produced assignments: 10 per cent.

To pass the module, a mark of 5/10 is required.

Ordinary examination period: students who do not achieve 5/10 points for the course must sit the exam for the mid-term exam or exams they have failed.

Extraordinary examination session: Students who do not pass the module in the ordinary examination session must sit the failed mid-term exam(s) in the extraordinary examination session in July.

Timetable

Click on this link to view the detailed timetable in Excel

Bibliography

Basic:

1. Benito Jiménez, César

360 Problems in Genetics:

: Síntesis. 1999.

ISBN: 8477385327

2. Benito, Espino

Genetics: Essential Concepts

Panamericana. 2013.

ISBN: 9788498354072

3. Griffiths, A.J.

Genetics

7th ed. Madrid [etc.]: McGraw-Hill Interamericana, 2002. 2002.

ISBN: 8448603680

4. Klug WS

Concepts of Genetics

8th ed. Pearson. 2006.

ISBN: 8420550140

5. Ménsua Fernández, José Luis

Genetics

: Pearson Educación. 2003.

ISBN: 8420533416

6. Pierce BA

Genetics: A Conceptual Approach

PANAMERICANA (3rd ed.). 2009.

ISBN: 9788498352160

Objectives

The main objective of the course is to integrate knowledge relating to the field of immunology within the field of biotechnology. To this end, the specific objectives are:

- To familiarise students with the constituent elements of the immune system and how they interact in the development of an immune response.

- To acquire knowledge of the molecular and cellular basis of the most relevant human immunological disorders.

- To provide knowledge of the most effective methods of prevention (passive immunisation, vaccines) and treatment (immunomodulation) of diseases.

- To acquire knowledge and understanding of the principles underpinning immunological techniques for the detection and characterisation of pathologies, as carried out in clinical/immunological laboratories in hospitals, pharmaceutical laboratories or research centres.

- Students should be able to handle immunology laboratory equipment skilfully.

- Students should learn to use the main bibliographic sources.

Competencies

CORE COMPETENCIES:

CB1: Students should have demonstrated that they possess and understand knowledge in an area of study building on the foundations of general secondary education; this is typically at a level which, whilst drawing on advanced textbooks, also includes some aspects requiring knowledge from the cutting edge of their field of study.

CB2: Students should be able to apply their knowledge to their work or profession in a professional manner and possess the skills typically demonstrated through the formulation and defence of arguments and the resolution of problems within their field of study.

CB3: Students should be able to gather and interpret relevant data (usually within their field of study) in order to form judgements that include reflection on relevant social, scientific or ethical issues.

CB4: Students should be able to communicate information, ideas, problems and solutions to both specialist and non-specialist audiences.

CB5: Students should have developed the learning skills necessary to undertake further study with a high degree of autonomy.

GENERAL COMPETENCIES:

CG1 – Ability to think in an integrated manner, to reason critically and to approach problems from different perspectives. /GC1 – Ability to think in a multi-level way, to develop critical questioning and to tackle problems from different perspectives.

CG2 – The ability to gather, process, interpret, analyse and synthesise relevant information and results, and to draw conclusions on topics related to biotechnology. / GC2 – The ability to gather, process, interpret, analyse and synthesise relevant information and results, and to draw conclusions on topics related to biotechnology.

CG3 – The ability to access and use international information sources, as well as to communicate in a foreign language of international relevance. / GC3 – Ability to access and use international information sources and to communicate in a relevant foreign language.

CG4 - Interpreting experimental results and identifying consistent and inconsistent elements. / GC4 - Capacity to interpret experimental results and to identify consistent and inconsistent elements.

CG5 – Apply the theoretical and practical knowledge acquired to problem-solving and seek solutions effectively and creatively in both professional and academic contexts. / GC5 – Ability to apply the acquired theoretical and practical knowledge to problems and to find effective and creative solutions in both professional and academic contexts.

CG6. – Ability to assimilate new concepts and learn independently, to organise and plan one’s work, and to develop the ability to work as part of a team and build self-confidence. / GC6 - Capability to assimilate new concepts and learn independently, to organise and plan one’s own work, and to be a self-confident team player.

SPECIFIC COMPETENCIES:

CE2. – Ability to work appropriately in a laboratory by applying the basic principles of safety, handling and waste disposal, and by keeping a detailed record of activities. / SC2 – Being able to work in a laboratory in a proper manner, i.e. applying the basic principles of handling and waste disposal, safety, and always keeping a record of activities.

CE15.- Distinguishing between the types of immune response and the function of the cells involved; knowing how to carry out basic immunological techniques and interpret the results obtained, as well as understanding the biotechnological applications based on the use of antibodies. / SC15 - Being able to identify the different types of immune response and the function of the cells involved; knowing how to perform basic immunological techniques and interpret their results, as well as understanding the biotechnological applications based on the use of antibodies.

Learning outcomes

• To acquire theoretical and practical knowledge of the genetic and molecular basis of the immune system.

• To identify immune cells and correlate their functions with immune responses.

• To distinguish between innate and adaptive immune responses.

• To identify the organs involved in the immune response and their functions.

Course description

SYLLABUS FOR MASTER CLASSES:

PHYSIOLOGY OF THE IMMUNE SYSTEM

Lesson 1. INTRODUCTION TO IMMUNOLOGY

Lesson 2. COMPONENTS OF THE IMMUNE SYSTEM

Lesson 3. Innate Immunity against Extracellular and Intracellular Pathogens

Lesson 4. Adaptive Immunity I: Antigen Recognition

Lesson 5. Adaptive Immunity II: Generation and Maturation of T and B Cells

Lesson 6. ADAPTIVE IMMUNITY III: ACTIVATION AND FUNCTION OF LYMPHOID CELLS

IMMUNOPATHOLOGY: CELLULAR AND MOLECULAR BASES

Lesson 7. DEFECTS OF THE IMMUNE SYSTEM: IMMUNODEFICIENCIES

Lesson 8. EXCESSIVE RESPONSE: HYPERSENSITIVITY AND ALLERGY

Lesson 9. ERRORS OF THE IMMUNE SYSTEM: AUTOIMMUNITY

Lesson 10. IMMUNE RESPONSE AGAINST TUMOURS

IMMUNOLOGICAL TECHNIQUES AND BIOTECHNOLOGY

Lesson 11. ARTIFICIAL IMMUNISATION: PASSIVE IMMUNISATION AND VACCINES.

Lesson 12. IMMUNE SYSTEM MODULATION: TRANSPLANTS

SUPPLEMENT TO MASTER CLASSES:

Various sessions on specific topics relating to the immune system:

- Cytokines and immune modulation

- Inflammation: a central role in various immune responses

- SARS-CoV-2 and the immune system

- Pathogens’ defence mechanisms against the immune system

- Modulation of the immune system during pregnancy

SEMINARS:

Work carried out by students on various aspects of the immune system

The work will be divided into three parts:

Oral presentation (using PowerPoint/Prezi/Keynote, etc.)

Brief summary of the talk (4–5-page Word document)

2 multiple-choice questions (similar to the mid-term test)

The mark obtained by the student in the seminar accounts for 15 per cent of the final mark for the module

PRACTICAL CLASSES:

Laboratory sessions will take place once a week

Two different groups/timetables: 14:30–17:30 and 17:30–20:30

4 laboratory sessions (Monday to Thursday):

Assessment of haemolytic complement activity (CH50)

Leukocyte isolation

Antigen determination by ELISA

Antibody detection by indirect immunofluorescence (IIF)

1 laboratory test (Friday):

This mark accounts for 15% of the final mark for the module

Teaching activities

Lectures/Sessions (SESSION in the timetable)

Laboratory sessions (LB on the timetable)

Seminars/Assignments (TRAB on the timetable)

Tutorials/Consultations/Lecture supplements (CN on the timetable)

Assessment (EV on the timetable)

Self-study

Assessment system and criteria

Without prejudice to any other requirements that may be specified in the relevant course syllabus, as a general rule, failure to attend more than 70 per cent of the course’s teaching activities—which require the student’s physical or virtual presence—will result in the loss of the right to continuous assessment during the standard examination period. In this case, the examination to be held during the official period set by the University will be the sole assessment criterion, with the weighting specified in the course syllabus.

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A) 2 mid-term tests to be taken online in the classroom

Characteristics of the mid-term test:

- Multiple-choice test

- 30 questions (5 options, 1 correct answer per question)

20 correct answers are required to pass the exam. Once a test has been passed, the corresponding topic is excluded from the ordinary assessment

B) Regular assessment:

To be taken online in the classroom

Features:

Multiple-choice test

30 questions (5 options, 1 correct answer per question) for students who have taken only one mid-term test. 20 correct answers are required to pass the exam

50 questions (5 options, 1 correct answer per question) for students covering the full syllabus; 30 correct answers are required to pass the exam

The final mark for the subject, provided that the theoretical part has been passed, is calculated as follows: 70% of the mark obtained in the theoretical part + 15% from the practical exam + 15% from the seminar mark

Timetable

Click on this link to view the detailed timetable in Excel

Reading list

Core:

1. Abbas MBBS, Abul K.; Lichtman MD PhD, Andrew H

Cellular and Molecular Immunology (10th Edition)

Elsevier. 2021.

ISBN: 9780323757485

2.- Murphy, K. — Weaver, C.

Janeway’s Immunobiology

NORTON MEDICAL BOOKS. 2017.

ISBN: 9780815345510

3. Peter J. Delves, Seamus J. Martin, Dennis R. Burton, Ivan M. Roitt

Roitt’s Essential Immunology 13th ed.

Wiley. 2017.

ISBN: 9781118415771

Objectives

An introduction to the structural study of organic compounds, their nomenclature systems and basic concepts of biochemistry, with a view to acquiring the following:

KNOWLEDGE

• A thorough understanding of the nomenclature and symbols used in organic chemistry.

• To understand the structure, nomenclature and reactivity of the main organic compounds.

• To have a good understanding of the concept of chirality and the conformation of organic molecules.

• To understand the basic principles of the mechanisms of organic reactions.

• Have a thorough understanding of the fundamentals of the structure and reactivity of the main biomolecules.

SKILLS

• Write chemical formulae for biologically relevant organic compounds and evaluate their main reactivity characteristics by relating them to their structural properties.

• Apply the concepts of stereochemistry and chirality to simple biomolecules.

• Relate the various mechanisms of organic reactions to biological processes

Competencies

BASIC COMPETENCIES

CB1: Students should have demonstrated that they possess and understand knowledge in an area of study building on the foundations of general secondary education; this is typically at a level which, whilst drawing on advanced textbooks, also includes some aspects requiring knowledge from the cutting edge of their field of study.

CB2: Students should be able to apply their knowledge to their work or profession in a professional manner and possess the skills typically demonstrated through the formulation and defence of arguments and the resolution of problems within their field of study.

CB3: Students should be able to gather and interpret relevant data (usually within their field of study) in order to form judgements that include reflection on relevant social, scientific or ethical issues.

CB4: Students should be able to communicate information, ideas, problems and solutions to both specialist and non-specialist audiences.

CB5: Students should have developed the learning skills necessary to undertake further study with a high degree of autonomy.

GENERAL COMPETENCIES

CG1 – To think in an integrated manner, reason critically and approach problems from different perspectives.

CG2 – Be able to obtain, process, interpret, analyse and synthesise relevant information and results, and draw conclusions on topics related to biotechnology.

CG4 – Interpret experimental results and identify consistent and inconsistent elements.

CG5 – Apply the theoretical and practical knowledge acquired to problem-solving and seek solutions effectively and creatively in both professional and academic contexts.

CG6 – Study and learn independently, organising and planning one’s work, and develop the ability to work in a team and build self-confidence.

SPECIFIC COMPETENCIES

CE1. – To know and understand the basic concepts of Mathematics, Physics, Chemistry and Biology, as well as the main tools used in these disciplines for research and the development of biotechnological processes.

CE2. – Work appropriately in a laboratory, applying the basic principles of safety, handling and waste disposal, and keeping a detailed record of activities.

CE3 – To be familiar with the main transformations of biomolecules, both in natural products and in their industrial derivatives, and to be able to carry out chemical reactions of biotechnological interest on a laboratory or industrial scale.

Learning outcomes

- Be able to recognise the functional groups of an organic compound or biochemical molecule.

- Understand the three-dimensional structure of molecules and its implications.

-Ability to design and interpret chemical transformations of organic compounds of interest in biotechnology.

- Be able to correlate the structure of organic and biochemical compounds with their physical properties, reactivity and stability.

-Understand the structure-activity relationship (SAR) of organic compounds of biochemical, pharmacological and/or environmental interest.

-Be familiar with the laboratory processes required for the transformation, separation, isolation and purification of organic compounds, whilst assessing the potential associated risks.

-Ability to apply the knowledge acquired in theory and laboratory practicals to the resolution of problems and issues relating to organic compounds.

-Preparing reports, summaries and presentations on bibliographic or experimental work, applying critical and self-critical thinking.

Description of the content

TOPIC 1. Introduction and general concepts.

TOPIC 2. NOMENCLATURE OF HYDROCARBONS

2.1. Nomenclature of alkanes and cycloalkanes.

2.2. Nomenclature of alkenes and alkynes.

2.3. Nomenclature of aromatic hydrocarbons: benzene and derivatives.

TOPIC 3. ISOMERY. STEREOCHEMISTRY

3.1. Structural isomers.

3.2. Spatial isomers. Stereoisomerism.

3.2.1. Diastereoisomers.

3.2.1.1. Cis-trans and E-Z geometric isomers.

3.2.2. Enantiomers or optical isomers.

TOPIC 4. NOMENCLATURE OF FUNCTIONAL GROUPS.

4.1. Nomenclature of alcohols, phenols and ethers.

4.2. Nomenclature of aldehydes and ketones.

4.3. Nomenclature of carboxylic acids and derivatives.

4.4. Nomenclature of nitrogen-containing compounds.

TOPIC 5. BASIC REACTIONS OF FUNCTIONAL GROUPS AND THEIR MECHANISMS.

5.1. General concepts.

5.2. Reactions of alkanes

5.3. Reactions of alkenes.

5.4. Cycloaddition reactions. Allylic systems and conjugated dienes.

5.5. Reactions of alkyne.

5.6. Reactions of halogenated derivatives. Substitution and elimination reactions.

5.7. Reactions of the carbonyl group.

5.8. Reactions of the carboxyl group.

5.9. Nucleophilic reactions of enolate anions.

TOPIC 6. AROMATIC ELECTROPHILIC SUBSTITUTION REACTIONS.

6.1. Basic substitution reactions.

6.2. Reaction mechanisms.

6.3. Reactivity and orientation in substituted benzenes.

6.4. Nucleophilic aromatic substitution reactions.

TOPIC 7. PROTECTIVE GROUPS FOR THE MAIN FUNCTIONAL GROUPS.

7.1. Protecting groups for alcohols and diols.

7.2. Protecting groups for aldehydes and ketones.

7.3. Protecting groups for carboxylic acids.

7.4. Protecting groups for amines.

Training activities

Lecture/Sessions (SESSION in the timetable)

Laboratory sessions (LB on the timetable)

Seminars/Assignments (TRAB on the timetable)

Tutorials/Consultations/Lecture supplements (CN on the timetable)

Assessment (EV on the timetable)

Self-study

Assessment system and criteria

Without prejudice to any other requirements that may be specified in the relevant course syllabus, as a general rule, failure to attend more than 70 per cent of the course’s teaching activities—which require the student’s physical or virtual presence—will result in the loss of the right to continuous assessment during the standard examination period. In this case, the examination to be held during the official period set by the University will be the sole assessment criterion, with the weighting specified in the course syllabus.

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Face-to-face final assessment

Participation in forums and other participatory activities: assessed on the basis of the student’s use of and participation in face-to-face and virtual sessions, workshops, forums, etc.

Practical assessment: designed to put into practice the concepts studied in each module. Assessment of this knowledge takes place at the end of the module in person.

Seminars: this criterion assesses the work students submit via the virtual classroom (assignments, projects, case studies) as well as in-class presentations

Timetable

Click on this link to view the detailed timetable in Excel

Bibliography

Core:

1. David Klein

Organic Chemistry

Panamericana. 2014.

ISBN: 9788498351699

2. Ege

Organic Chemistry

Reverté. 2000.

ISBN: 8429170650

3. García, F. and Dobado, J. A.

Solved Problems in Organic Chemistry

Paraninfo. 2007.

ISBN: 8497324587

4. McMurry, John

General Chemistry

Mexico: Pearson Educación, 2009. 2009.

ISBN: 9780131993235

5. Quiñoá Cabana, Emilio

Organic Chemistry Questions and Exercises: A Study Guide

Madrid: McGraw-Hill Interamericana de España, 200. 2004.

ISBN: 844814015X

6. Quiñoá, Emilio

Nomenclature and Formulation of Inorganic Compounds: U

Madrid [etc.]: McGraw-Hill, 2006. 2006.

ISBN: 8448146255

7. Solomons, T. W. Graham

Organic Chemistry

Mexico City: Limusa Wiley, 2000. 2000.

ISBN: 9681852176

8. Solomons, T. W. Graham

Organic Chemistry: Study Guide and Answers

Mexico City: Limusa Wiley, 1999. 1999.

ISBN: 9681845609

9. Vollhardt, K. Peter C.

Organic Chemistry: Structure and Function

Barcelona: Omega, 2000. 2000.

ISBN: 8428211728

Supplementary:

10.- Carey, Francis A.

Organic Chemistry

Madrid [etc.]: McGraw-Hill, 1999. 1999.

ISBN: 844812426X

11.- Isac-García

Experimental Organic Chemistry

Elsevier. 2015.

ISBN: 9780128038932

12. Wade, L.G.

Organic Chemistry

Pearson Prentice Hall. 2004.

ISBN: 8420541028

13. Warren, Stuart

Solution Manual to Accompany Organic Chemistry

Oxford: Oxford University Press, 2001. 2001.

ISBN: 0198700385

Objectives

- To learn about and understand the various basic principles underpinning instrumental techniques.

- To demonstrate knowledge of how basic analytical instrumentation works.

- To acquire the ability to operate the various instruments and adjust instrumental variables, as well as to extract the greatest amount of reliable information from experimental data.

- To develop proficiency in the instrumental techniques most commonly used in biotechnology and to be able to select the most suitable ones for a specific biotechnological process.

- To understand biolabelling techniques.

Competencies

BASIC COMPETENCIES:

CB1: Students should have demonstrated that they possess and understand knowledge in an area of study building on the foundations of general secondary education; this is typically at a level which, whilst drawing on advanced textbooks, also includes certain aspects requiring knowledge from the cutting edge of their field of study.

CB2: Students should be able to apply their knowledge to their work or profession in a professional manner and possess the skills typically demonstrated through the development and defence of arguments and the resolution of problems within their field of study.

CB3: Students should be able to gather and interpret relevant data (usually within their field of study) in order to form judgements that include reflection on relevant social, scientific or ethical issues.

CB4: Students should be able to communicate information, ideas, problems and solutions to both specialist and non-specialist audiences.

CB5: Students should have developed the learning skills necessary to undertake further study with a high degree of autonomy.

GENERAL COMPETENCIES:

CG1: To think in an integrated manner, reason critically and approach problems from different perspectives.

CG2: Be able to obtain, process, interpret, analyse and synthesise relevant information and results, and draw conclusions on topics related to biotechnology.

CG4: To interpret experimental results and identify consistent and inconsistent elements.

CG5: Apply the theoretical and practical knowledge acquired to problem-solving and seek solutions effectively and creatively in both professional and academic contexts.

CG6: Study and learn independently, organising and planning one’s work, and develop the ability to work in a team and build self-confidence.

SPECIFIC COMPETENCIES:

CE2: Work appropriately in a laboratory by applying the basic principles of safety, handling and waste disposal, and by keeping a detailed record of activities.

CE8: Understand and be able to apply instrumental techniques and working protocols in biotechnology laboratories, as well as acquire skills in the handling of equipment.

Learning outcomes

• Understand the various basic principles underpinning instrumental techniques.

• Demonstrate knowledge of how basic analytical instruments operate.

• Acquire the ability to operate the various instruments and adjust instrumental variables, as well as to extract the greatest amount of reliable information from experimental data.

• To acquire proficiency in the instrumental techniques most commonly used in biotechnology and to know how to select the most suitable ones for a specific biotechnological process.

• To describe the theoretical foundations of the basic techniques for the isolation and characterisation of biomolecules.

Course content

1. Introduction to Instrumental Techniques

2. Optical Techniques

- Flame spectroscopy. ICP-OES

- UV-Vis absorption spectroscopy

- Fluorescence and phosphorescence spectroscopy

- Turbidimetry

- Other non-spectroscopic techniques

3. Enzymatic assays

4. Radioactive labelling of biomolecules

5. Electrochemistry

- Potentiometry

- Voltammetry

6. Sensors and biosensors

7. Centrifugation

- Ultracentrifugation

LABORATORIES:

- UV-Vis spectroscopy

- Potentiometry

- Centrifugation

Training activities

Lecture/Sessions (SESSION in the timetable)

Laboratory sessions (LB on the timetable)

Seminars/Assignments (TRAB on the timetable)

Tutorials/Consultations/Complements to lectures (CN on the timetable)

Assessment (EV on the timetable)

Self-study

Assessment system and criteria

Without prejudice to any other requirements that may be specified in the relevant course syllabus, as a general rule, failure to attend more than 70 per cent of the course’s teaching activities—which require the student’s physical or virtual presence—will result in the loss of the right to continuous assessment during the standard examination period. In this case, the examination to be held during the official period set by the University will be the sole assessment criterion, with the weighting specified in the course syllabus.

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1. Mid-term exams – 70%

- First mid-term exam: 35% (covers 5.0 and exempts 6.5)

- Second mid-term exam: 35% (covers a mark of 5.0 and exempts a mark of 6.5)

2. Laboratory work - 15%

3. Assignments – 15%

Timetable

Click on this link to view the detailed timetable in Excel

Bibliography

Essential:

1. Skoog, Douglas A.

Principles of Instrumental Analysis

Madrid [etc.]: McGraw-Hill, 2000. 2000.

ISBN: 8448127757

Objectives

1. To understand and explain the main signalling pathways involved in developmental processes.

2. To understand the stages and factors involved in gametogenesis and sporogenesis.

3. To understand the stages and factors involved in the processes of fertilisation and implantation.

4. To understand the processes involved in early embryonic development.

5. To understand the processes involved in the formation of the body plan during development, morphogenesis and organogenesis.

6. To understand the mechanisms involved in tissue regeneration.

7. To understand the characteristics and functions of animal and plant tissues.

8. To identify different plant and animal tissues under a microscope.

9. Recognise embryonic structures by observing samples under a microscope.

10. Practise, under supervision, basic techniques for handling chicken embryos (Gallus domesticus).

Competencies

BASIC COMPETENCIES:

CB1 – Students have demonstrated that they possess and understand knowledge in an area of study building on the foundations of general secondary education; this is typically at a level which, whilst drawing on advanced textbooks, also includes some aspects requiring knowledge from the cutting edge of their field of study.

CB2 – Students should be able to apply their knowledge to their work or profession in a professional manner and possess the skills typically demonstrated through the formulation and defence of arguments and the resolution of problems within their field of study.

CB3 – Students should be able to gather and interpret relevant data (usually within their field of study) in order to form judgements that include reflection on relevant social, scientific or ethical issues.

CB4 – Students should be able to communicate information, ideas, problems and solutions to both specialist and non-specialist audiences.

CB5 – Students should have developed the learning skills necessary to undertake further study with a high degree of autonomy.

GENERAL COMPETENCIES:

CG1 - To think in an integrated manner, reason critically and approach problems from different perspectives.

CG2 - Be able to obtain, process, interpret, analyse and synthesise relevant information and results, and draw conclusions on topics related to biotechnology.

CG3 – Be able to use international sources of information and to communicate in a second language of international relevance.

CG4 - Interpret experimental results and identify consistent and inconsistent elements.

CG5 - Apply the theoretical and practical knowledge acquired to problem-solving and seek solutions effectively and creatively in both professional and academic contexts.

CG6 - Study and learn independently, organising and planning one’s work, and develop the ability to work in a team and build self-confidence.

SPECIFIC COMPETENCIES:

CE1 - To know and understand the basic concepts of Mathematics, Physics, Chemistry and Biology, as well as the main tools used in these disciplines for research and the development of biotechnological processes.

CE2 – Work appropriately in a laboratory by applying the basic principles of safety, handling and waste disposal, and by keeping a detailed record of activities.

CE10 – To understand the processes of morphogenesis and cell communication that regulate the development, differentiation and proliferation of plant and animal tissues

Learning outcomes

- Be able to identify and describe the stages and factors involved in the processes of sporogenesis, gametogenesis, fertilisation and early embryonic development.

- Be able to identify and describe the processes that determine the morphogenesis of tissues and body structures, the formation of the body plan and the capacity for regeneration.

- List the characteristics and functions of the various plant and animal tissues.

- Identify the different plant and animal tissues using an optical microscope.

Description of the content

1. INTRODUCTION TO DEVELOPMENTAL BIOLOGY

2. CONCEPTUAL TOOLS

3. BASIC CONCEPTS OF MOLECULAR SIGNALLING IN DEVELOPMENT

4. GAMETOGENESIS

5. FERTILISATION, SEGMENTATION AND BLASTOGENESIS

6. ESTABLISHMENT OF THE BODY PLAN IN VERTEBRATES

7. MORPHOGENESIS: CHANGES IN THE SHAPE OF THE EARLY EMBRYO

8. ORGANOGENESIS

9. TISSUE REGENERATION

10. PLANT DEVELOPMENTAL BIOLOGY

Training activities

Lecture/Sessions (SESSION in the timetable)

Laboratory sessions (LB on the timetable)

Seminars/Assignments (TRAB on the timetable)

Tutorials/Consultations/Lecture supplements (CN in the timetable)

Assessment (EV on the timetable)

Self-study

Assessment system and criteria

Without prejudice to any other requirements that may be specified in the relevant course syllabus, as a general rule, failure to attend more than 70 per cent of the course’s teaching activities—which require the student’s physical or virtual presence—will result in the loss of the right to continuous assessment during the standard examination period. In this case, the examination to be held during the official period set by the University will be the sole assessment criterion, with the weighting specified in the course syllabus.

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ASSESSMENT CRITERIA

ASSESSMENT SYSTEM

1. THEORY (LECTURES + ASSIGNMENTS): 60%

2. LABORATORY PRACTICALS: 30%

3. CONTINUOUS ASSESSMENT: 10% added to the mark for each exam

THEORY ASSESSMENT

1. During the course, there will be two eliminatory mid-term exams.

2. These exams will also include questions from the seminars.

3. The exams are multiple-choice. They will consist of 30 questions, each with four options, only one of which is correct. Incorrect answers will result in a deduction of 0.11. A pass is achieved with a mark of 5 out of 10.

4. The theory mark will be the average of the two mid-term exams, provided that the mark for both mid-term exams is at least 4 out of 10.

5. If the average mark for the mid-term exams is below 5, if any mid-term exam has a mark below 4, or if a student is marked ‘NP’ (did not sit the exam), they will have to retake the failed mid-term exam(s) in the Ordinary Examination Period (January).

6. If, following the Ordinary Examination Period, the mark is still below 5, the student will be required to retake the failed mid-term exam(s) during the Extraordinary Examination Period (May/June).

LABORATORY ASSESSMENT

1. The laboratory practicals consist of FIVE SESSIONS.

2. The exam will be a multiple-choice test comprising 30 questions, each with four options, only one of which is correct. Incorrect answers result in a deduction of 0.11. A pass is achieved with a mark of 5 out of 10.

3. Attendance at and sitting of the laboratory examinations IS COMPULSORY FOR ALL STUDENTS. Each instance of unexcused absence during the practical sessions results in a deduction of 25 per cent from the laboratory mark.

4. Failure to undertake the practical sessions will result in a fail for the laboratory module and the course.

5. Students who have attended the practical sessions but have not passed the exam must retake the laboratory multiple-choice exam during the Ordinary Examination Period.

6. Failing the Ordinary Examination Session means that the laboratory multiple-choice exam must be retaken in the Extraordinary Examination Session.

CONTINUOUS ASSESSMENT

1. This will consist of the submission of TWO ASSIGNMENTS via the course platform and student participation.

2. Students may add up to 10% of the continuous assessment mark to their theory mark, provided that the mark obtained in the theory component is 4 or above.

Timetable

Click on this link to view the detailed timetable in Excel

Bibliography

Basic:

1. Arteaga Martinez

Human Embryology and Developmental Biology

Panamericana. 2021.

ISBN: 6078546465

2. Keith L. Moore

Clinical Embryology

Elsevier. 2014.

ISBN: 8480869763

3. Scott F. Gilbert

Developmental Biology

SINAUER. 2003.

ISBN: ‎ 0197574610

4. Wolpert

Principles of Development

Panamericana. 2010.

ISBN: 8498352061