Most searched curriculums

Official qualification

Oviedo

Degree in Medicine*.

+ Advanced CPR Diploma

Prepare yourself to practice the medicine of the future with the first university that includes high-level training in Digital Health. At UAX you will learn in the largest Virtual Simulation Hospital in Europe through real cases, you will be able to do your rotations in more than 38 services in prestigious hospitals and access a specific training plan for the MIR in the last years of your career.

No. 1 among all private universities in Spain where the best doctors are trained, according to ConSalud.

*Degree that appears in Decree 110/2025, of 14 October, of the Principality of Asturias, authorising the assignment of the Alfonso X El Sabio Asturias University Centre to the Alfonso X El Sabio University. Degree in the process of modification for its teaching in the aforementioned Affiliated Centre in the 26/27 academic year.

Last few places

Start September

Length Credits 6 years / 360 ECTS

Language Spanish

Modality On-campus

Campus Oviedo / Villanueva de la Cañada

Faculty Biomedical and Health Sciences / Alfonso X el Sabio University Centre, Asturias.

In collaboration with:

Study medicine and immerse yourself in your future career with 1,680 hours of practical training and the latest developments in healthcare.

At UAX, we train you with a view to practising in 10 years’ time, in the medicine of the future.

Study with an innovative curriculum, so that the knowledge you gain today won’t be left behind tomorrow. The UAX Faculty of Medicine is the first in Spain to include training in Digital Medicine: telemedicine, patient care via apps and wearables, data analysis, predictive and preventative medicine, digital management of waiting lists, etc.

An environment featuring a Virtual Hospital and advanced simulation facilities.

Equipped with the latest systems for clinical simulation, surgical training, clinical reasoning, decision-making software, advanced laboratories, etc.

- Body Interact: an interactive table for tackling real clinical situations with virtual patients.

- Practicum Script: a programme to train your clinical reasoning and build confidence in decision-making.

- SECTRA Portal: this will give you a better understanding of anatomy by tackling real cases and studying
high-resolution radiological and histological images.

- Human dissection room

- Specialised laboratories

Specific MIR preparation programme: 96% pass rate in the exam.

Throughout your degree, you’ll be able to prepare for the MIR exam by taking part in workshops, tests and mock exams, giving you a head start. At our UAX Faculty of Medicine, we have trained over 400 medical professionals, and more than 90% are currently undertaking their MIR specialisation at the best hospitals in Spain.

Rotations across more than 38 specialities

At UAX, you’ll be able to undertake rotations across almost all departments and specialities, helping you discover the area you enjoy most. We have agreements with a number of the city’s hospitals, both public and private: Vital Álvarez Buylla, Clínica Asturias, Begoña Hospital, Gijón Hospital, Covadonga Hospital… and many more.

UAX Medicine Rankings on Consalud

- Among the top 5 private universities in Spain for studying Medicine: These are the five best private universities in Spain for studying Medicine | ConSalud

-Best universities for studying medicine in the world and in Spain: Here is the ranking of the best universities for studying medicine in the world and in Spain | ConSalud

UAX Skill School Professional Certificate

At UAX, you’ll acquire the skills most in demand by hospitals and leading healthcare organisations, gaining certifications in: Analytical Thinking, Leadership & Ethics, Working in Agility & Diverse Teams, Storytelling and Disruptive Thinking.

Connected to the world of work

From the very first day of your medical degree, you’ll be connected to the professional world through seminars, workshops and work placements that count towards your degree, allowing you to put everything you’ve learnt into practice.

Information on the Bachelor’s Degree in Medicine

Curriculum

Bachelor’s Degree in Medicine

First Year

ANNUAL SUBJECTS

Code

Subjects

Character*

ECTS

N10200

Morphology, Structure and Function of Organs and Systems I

Código: N10200 Imprimir

Year 1. Annual module. Foundation course. 9 credits.

Profesores

Luis Matesanz Garcia - Coordinador	Ver biodata European Doctorate in Health Sciences and Biomedicine from Rey Juan Carlos University, where he was awarded the grade of Distinction Cum Laude, the Extraordinary Doctoral Award and various honours for his thesis on entrapment neuropathies and neuropathic pain. His research focuses on the pathophysiology of peripheral neuropathic pain, the identification of biomarkers, the mechanisms of sensitisation and the development of personalised treatments through therapeutic exercise and other conservative interventions. She has an outstanding record of scientific publications in high-impact international journals such as PAIN, The Journal of Pain, Journal of Neuroimmunology or Neuromodulation,Musculoskeletal Science and Practice. Furthermore, he participates in established research groups, competitive projects and the supervision of doctoral theses relating to pain and peripheral neuropathies. At an international level, he undertook a three-month research placement at the University of Oxford (Nuffield Department of Clinical Neurosciences) and was a visiting lecturer at the University of Ljubljana (Slovenia), where he delivered the seminar Assessment and Treatment of Peripheral Nerve Disorders and established new scientific collaborations. He has also taken part in international teaching initiatives with the Autonomous University of Manizales (Colombia) on the assessment and treatment of peripheral nerve disorders. has delivered over 1,000 hours of teaching at undergraduate and postgraduate level in the fields of physiotherapy, pharmacology, therapeutic exercise and pain, as well as supervising undergraduate dissertations and co-supervising doctoral theses. She has been awarded the Juan Antonio Micó Prize for the Best Doctoral Thesis on Pain, and the Prize for the Best Doctoral Thesis from the Madrid Professional Association of Physiotherapists
Álvaro Iglesias Puzas	Ver biodata Álvaro Iglesias Puzas holds a Doctorate in Medicine from the Complutense University of Madrid, with the distinction ‘Sobresaliente Cum Laude’, and is a specialist in Dermatology. He holds a degree in Medicine and Surgery from the University of Santiago de Compostela, he completed his residency training at the Pontevedra University Hospital Complex and has pursued his career as a specialist physician at leading centres such as the Hospital Clínico San Carlos in Madrid and the MD Anderson Cancer Centre, where he specialised in oncological dermatology, dermatological surgery and Mohs surgery. He currently practises at the Álvarez Buylla Hospital in Mieres. His academic profile is complemented by several official master’s degrees in clinical research, healthcare leadership and clinical management, as well as a number of university-specific qualifications. He is accredited by ANECA as a Contracted Doctoral Lecturer and a Lecturer at a private university. In the field of teaching, he has served as an Associate Professor of Dermatology at the Complutense University of Madrid, receiving an ‘Excellent’ rating for his teaching in the Docentia programme. He has supervised numerous final-year dissertations, which have received outstanding marks, and has delivered numerous presentations and training sessions. His scientific output is extensive, comprising numerous articles published in national and international journals, book chapters and participation in research projects and clinical trials. He has been awarded prizes and grants from the European Academy of Dermatology. Furthermore, he serves as a reviewer for prestigious scientific journals and is a member of various national and international dermatological societies, bringing a solid combination of clinical, research and teaching excellence.
Cristina Magadán Álvarez	Ver biodata Bachelor of Medicine from the University of Cantabria (2007–2013), including an Erasmus placement at Ghent University (Belgium). Completed her MIR training in General and Gastrointestinal Surgery at the Marqués de Valdecilla University Hospital (2014–2019), including a placement as an International Research Fellow at NYU Winthrop Hospital (2017). Senior Registrar (FEA) in General and Gastrointestinal Surgery at San Agustín University Hospital (Avilés) since 2019. PhD from the University of Cantabria (2023), with a thesis on short- and long-term survival in hepatocellular carcinoma treated by resection or liver transplantation. Master’s degree in Breast Surgery from the University of Barcelona (2023). Author and co-author of publications in national and international scientific journals, including Annals of Surgery, British Journal of Surgery and Cirugía Española. Lecturer at San Agustín University Hospital and honorary lecturer at the University of Oviedo since 2019. She holds a Master’s in Teaching from Alfonso X el Sabio University (2026). She is the Undergraduate Medicine Programme Coordinator at the Alfonso X Asturias University Centre.
Eduardo Higueras Mora	Ver biodata A doctor qualified from the University of Alcalá. A specialist in Clinical Biochemistry and Pathological Anatomy, trained at the Central University Hospital of Asturias (HUCA). He has specific training and experience in Molecular Pathology, including specialist rotations in this field. He currently works as a Specialist in Pathological Anatomy at Cabueñes University Hospital, where he is in charge of Gastrointestinal Pathology.
Natalia Fontanil Vior	Ver biodata Graduated in Medicine from the Faculty of Oviedo in 2019 Specialist in Pathological Anatomy at the Asturias Medical Centre since 2024 Junior Registrar in Pathology at the Marqués de Valdecilla Hospital from 25 September 2020 to 24 September 2024 Master’s degree in continuing professional development in oncological pathology in 2025
Roberto Adrián Iglesias García	Ver biodata Graduated in Medicine from the Faculty of Oviedo in 2019 Specialist in Pathological Anatomy at the Asturias Medical Centre since 2024 Junior Registrar in Pathology at the Marqués de Valdecilla Hospital from 25 September 2020 to 24 September 2024 Master’s degree in continuing professional development in oncological pathology in 2025
Víctor Manuel Folgueras Henriksen	Ver biodata Graduated in Medicine from the Faculty of Oviedo in 2019 Specialist in Pathological Anatomy at the Asturias Medical Centre since 2024 Junior Registrar in Pathology at the Marqués de Valdecilla Hospital from 25 September 2020 to 24 September 2024 Master’s degree in continuing professional development in oncological pathology in 2025
Marlene Eloisa Alvarez Rico	Ver biodata Graduated in Medicine from the Faculty of Oviedo in 2019 Specialist in Pathological Anatomy at the Asturias Medical Centre since 2024 Junior Registrar in Pathology at the Marqués de Valdecilla Hospital from 25 September 2020 to 24 September 2024 Master’s degree in continuing professional development in oncological pathology in 2025
Marta María Sánchez Menéndez	Ver biodata Bachelor of Medicine, Doctor of Medicine, University of Oviedo. Grade: First Class with Distinction (Cum Laude) Specialist in Rheumatology (MIR). F.E.A. Rheumatology, HUCA, 2009–2010. Junior Specialist in Rheumatology at the Asturias Medical Centre Hospital Postgraduate courses at the University of Oviedo. Department of Surgery and Medical-Surgical Specialities. Grade: First Class SER Master’s in Immune-Mediated Rheumatic Diseases. Rey Juan Carlos University Specialisation course in Osteoporosis and Metabolic Bone Diseases and in Pain Management. Open University of Catalonia Advanced level in Musculoskeletal Ultrasound. SER School of Ultrasound Visiting Lecturer. Department of Medicine and Health Sciences, University of Oviedo (2006–2008) Lecturer at the Padre Ossó Faculty, a centre affiliated with the University of Oviedo (2022–2026). Courses taught on the Bachelor’s Degree in Occupational Therapy: Human Anatomy I, Human Anatomy II, Geriatrics and Osteoarticular Pathologies. Academic coordinator for the modules Geriatrics and Osteoarticular Disorders (2025–2026) and Human Anatomy I (2022–2023) Research Trainee, Department of Rheumatology. Mayo Clinic, Rochester, Minnesota, USA (2010) PUBLICATIONS Arias-Guillén M, Sánchez Menéndez MM. High rates of tuberculin skin test positivity due to methotrexate therapy: False-positive results? Seminars in Arthritis and Rheumatism. 2018;48(3):538–546. doi:10.1016/j.semarthrit.2018.03.018. PMID: 2973517 ¿ Ernst FC, Sánchez-Menéndez M, et al. Cardiovascular risk profile at the onset of psoriatic arthritis: a population-based cohort study. Arthritis Care & Research (Hoboken). 2015;67(7):1015–1021 doi: 10.1002/acr.22536. PMID: 25581120. ¿ Cartin-Ceba R, Golbin JM, Keogh KA, Peikert T, Sánchez-Menéndez M, et al. Rituximab for remission induction and maintenance in refractory granulomatosis with polyangiitis (Wegener’s): a single-centre ten-year experience. Arthritis & Rheumatism. June 2012; 64(6):3770–3778. doi: 10.1002/art.34584. PMID: 2273002821. doi: 10.1002/art.34584.
María del Carmen Sánchez Blanco	Ver biodata Specialist in Gynaecology and Obstetrics Official Doctorate from the Doctoral Programme in Molecular and Cellular Biology at the University of Oviedo Lecturer at the Asturias MIR Academy Associate Lecturer at the University of Oviedo Master’s degree in Perinatal Diagnosis (2026) Master’s degree in Minimally Invasive Surgery Expert in the ultrasound diagnosis of endometrial pathology. Expert in the ultrasound diagnosis of ovarian pathology. Recent publications: Sánchez Blanco C, García Cancelo M, González Martínez C, Cardo González L, Diéguez Felechosa M. Current status of iodine intake in pregnant women in Asturias, Spain. Endocrinol Diabetes Nutr (Engl Ed). Dec 2025;72(10):501646. doi: 10.1016/j.endien.2025.501646. Epub 15 Oct 2025. PMID: 41102067. Martínez-Morillo E., Álvarez Rodríguez S., Muñoz Peña S., Sánchez Blanco C., Jiménez Mendiguchia L., Corte Arboleya Z., & Venta Obaya R. (2026). Comparison of Two Mathematical Models for the Screening of Pre-eclampsia Using Free Cloud Computing Resources. Applied Medical Informatics, 48(2), 58–66. - 66
Ángel Ramón Piñera Parrilla	Ver biodata Specialist in Gynaecology and Obstetrics Official Doctorate from the Doctoral Programme in Molecular and Cellular Biology at the University of Oviedo Lecturer at the Asturias MIR Academy Associate Lecturer at the University of Oviedo Master’s degree in Perinatal Diagnosis (2026) Master’s degree in Minimally Invasive Surgery Expert in the ultrasound diagnosis of endometrial pathology. Expert in the ultrasound diagnosis of ovarian pathology. Recent publications: Sánchez Blanco C, García Cancelo M, González Martínez C, Cardo González L, Diéguez Felechosa M. Current status of iodine intake in pregnant women in Asturias, Spain. Endocrinol Diabetes Nutr (Engl Ed). Dec 2025;72(10):501646. doi: 10.1016/j.endien.2025.501646. Epub 15 Oct 2025. PMID: 41102067. Martínez-Morillo E., Álvarez Rodríguez S., Muñoz Peña S., Sánchez Blanco C., Jiménez Mendiguchia L., Corte Arboleya Z., & Venta Obaya R. (2026). Comparison of Two Mathematical Models for the Screening of Pre-eclampsia Using Free Cloud Computing Resources. Applied Medical Informatics, 48(2), 58–66. - 66
José Ramón Méndez Álvarez	Ver biodata Specialist in Gynaecology and Obstetrics Official Doctorate from the Doctoral Programme in Molecular and Cellular Biology at the University of Oviedo Lecturer at the Asturias MIR Academy Associate Lecturer at the University of Oviedo Master’s degree in Perinatal Diagnosis (2026) Master’s degree in Minimally Invasive Surgery Expert in the ultrasound diagnosis of endometrial pathology. Expert in the ultrasound diagnosis of ovarian pathology. Recent publications: Sánchez Blanco C, García Cancelo M, González Martínez C, Cardo González L, Diéguez Felechosa M. Current status of iodine intake in pregnant women in Asturias, Spain. Endocrinol Diabetes Nutr (Engl Ed). Dec 2025;72(10):501646. doi: 10.1016/j.endien.2025.501646. Epub 15 Oct 2025. PMID: 41102067. Martínez-Morillo E., Álvarez Rodríguez S., Muñoz Peña S., Sánchez Blanco C., Jiménez Mendiguchia L., Corte Arboleya Z., & Venta Obaya R. (2026). Comparison of Two Mathematical Models for the Screening of Pre-eclampsia Using Free Cloud Computing Resources. Applied Medical Informatics, 48(2), 58–66. - 66
Jose Paz Aparicio	Ver biodata Specialist in Gynaecology and Obstetrics Official Doctorate from the Doctoral Programme in Molecular and Cellular Biology at the University of Oviedo Lecturer at the Asturias MIR Academy Associate Lecturer at the University of Oviedo Master’s degree in Perinatal Diagnosis (2026) Master’s degree in Minimally Invasive Surgery Expert in the ultrasound diagnosis of endometrial pathology. Expert in the ultrasound diagnosis of ovarian pathology. Recent publications: Sánchez Blanco C, García Cancelo M, González Martínez C, Cardo González L, Diéguez Felechosa M. Current status of iodine intake in pregnant women in Asturias, Spain. Endocrinol Diabetes Nutr (Engl Ed). Dec 2025;72(10):501646. doi: 10.1016/j.endien.2025.501646. Epub 15 Oct 2025. PMID: 41102067. Martínez-Morillo E., Álvarez Rodríguez S., Muñoz Peña S., Sánchez Blanco C., Jiménez Mendiguchia L., Corte Arboleya Z., & Venta Obaya R. (2026). Comparison of Two Mathematical Models for the Screening of Pre-eclampsia Using Free Cloud Computing Resources. Applied Medical Informatics, 48(2), 58–66. - 66
Leonor Meana Carballo	Ver biodata Specialist in Gynaecology and Obstetrics Official Doctorate from the Doctoral Programme in Molecular and Cellular Biology at the University of Oviedo Lecturer at the Asturias MIR Academy Associate Lecturer at the University of Oviedo Master’s degree in Perinatal Diagnosis (2026) Master’s degree in Minimally Invasive Surgery Expert in the ultrasound diagnosis of endometrial pathology. Expert in the ultrasound diagnosis of ovarian pathology. Recent publications: Sánchez Blanco C, García Cancelo M, González Martínez C, Cardo González L, Diéguez Felechosa M. Current status of iodine intake in pregnant women in Asturias, Spain. Endocrinol Diabetes Nutr (Engl Ed). Dec 2025;72(10):501646. doi: 10.1016/j.endien.2025.501646. Epub 15 Oct 2025. PMID: 41102067. Martínez-Morillo E., Álvarez Rodríguez S., Muñoz Peña S., Sánchez Blanco C., Jiménez Mendiguchia L., Corte Arboleya Z., & Venta Obaya R. (2026). Comparison of Two Mathematical Models for the Screening of Pre-eclampsia Using Free Cloud Computing Resources. Applied Medical Informatics, 48(2), 58–66. - 66

Objectives

˗ To understand the structural organisation of the human body and the morphological, embryological and histological foundations of the musculoskeletal system, the skin and its appendages, integrating the different levels of study (macroscopic, microscopic and embryonic development).

˗ To understand general embryonic development processes and their relationship to the origin of congenital anomalies, as well as the mechanisms of homeostasis and regulation that underpin the normal functioning of the systems and apparatuses studied.

˗ To identify, using macroscopic and microscopic methods and imaging techniques, the normal structures of the skin, its appendages and the musculoskeletal system at different stages of life, recognising their functional interrelationships.

Prerequisites

No specific prior knowledge is required, as this is a core first-year module. It is recommended that students have a general understanding of Biology and Chemistry at A-level.

Learning Outcomes

- RC19 - Recognise, diagnose and guide the management of the main skin conditions.

- RC31 - Recognise, diagnose and guide the management of the main disorders of the musculoskeletal system.

Learning Outcomes

˗ RK11 - Embryonic development and organogenesis

˗ RK12 - Understanding the morphology, structure and function of the skin

˗ RK16 - Understand the morphology, structure and function of the musculoskeletal system

˗ RK23 - Growth, maturation and ageing of the various systems and apparatus

˗ RK24 - Homeostasis

Description of the content

KNOW:

1. Morphology and function of muscle groups: trunk, head, neck and limbs.

2. Components of bones: organisation and general structure.

3. Types of joints. Morphology, structure and function of the different types of joints.

4. Vascularisation and innervation of the musculoskeletal system. Neuromuscular axes.

5. Morphology of the spine, pelvic girdle and shoulder girdle. Limbs. Skull and face.

6. Morphology and structure of the skin and its appendages at different stages of life.

7. Structure, distribution and function of epithelial, connective, muscular and nervous tissues.

8. Molecular mechanisms of embryonic development. Anomalies, terminology and causes of congenital abnormalities.

9. Gametogenesis: Oogenesis. Spermatogenesis.

10. Fertilisation.

11. Segmentation: formation of the morula and the blastula. Implantation.

12. Formation of the gastrula. Germ layers.

13. Characteristics and regulatory mechanisms of morphogenetic movements in the human embryo.

14. Characteristics and regulatory mechanisms of cell differentiation processes in the human embryo.

15. Structure and formation of the ectoderm, endoderm and mesoderm, and their differentiation.

16. Structure and formation of the foetal membranes.

17. Process and stages of embryo and foetal growth.

18. The process of embryonic development of the epidermis and the organs derived from it.

19. Embryonic development of the musculoskeletal system.

20. Function of the skin

21. Function of the hair follicle and sebaceous gland.

22. Function of the nail.

23. Function of the sweat glands.

24. Ageing of the skin.

25. Mechanisms of skin repair and adaptation.

26. Dynamic regulation and distribution of body water.

27. Body fluid compartments. Body volumes and composition. Water homeostasis.

28. General control mechanisms.

29. Molecular basis of muscle contraction and its regulation. Fatigue. Tetany.

30. Ultrastructure of the skin.

31. The process of keratinisation and pigmentation.

32. Ultrastructure of the hair follicle and sebaceous gland.

33. Ultrastructure of the nail.

34. Ultrastructure of the sweat glands.

35. Skin receptors.

36. Morphology and cellular and molecular structure of muscles and their components.

37. General structure and cell types of bone tissue.

38. Radiological examination of the musculoskeletal system: techniques, indications, basic semiology.

39. Bone densitometry.

PRACTICAL SKILLS

1. Recognise, using macroscopic methods and imaging techniques, the morphology and

various structures of the musculoskeletal system at different stages of life.

2. Recognise, using macroscopic methods and imaging techniques, the morphology and

structures of the skin and its appendages at different stages of life.

3. To identify, under supervision, the embryonic structures using an optical microscope.

4. To identify, under supervision, the different components of a

placental structure.

5. To identify, using macroscopic and microscopic methods and imaging techniques, the

morphology and various structures of the systems that make up the human body at

the various stages of ontogenetic development.

6. Understand the normal functions of the skin and its appendages.

7. To recognise, microscopically, the morphology and various structures of the skin and its

appendages at the various stages of life.

8. To identify, using microscopic methods, the morphology and various structures of the

locomotor system at different stages of life using microscopic methods.

Be able to perform competently (routinely and without supervision)

1. Identify normal anatomical structures and detect abnormalities in:

2. Plain X-rays of the chest, abdomen and bony structures.

Training activities

1. Lectures: Explanation of the theoretical foundations of the structural organisation of the human body, general embryology, and the morphology, structure and function of the skin and the musculoskeletal system, using IT tools and audiovisual resources.

2. Specialised seminars: on the content covered in the lectures, with active student participation and group discussion.

3. Laboratory practicals: Macroscopic and microscopic examination of structures of the musculoskeletal system and the skin and its appendages (anatomical dissection/prosection, optical microscopy of histological specimens and basic imaging techniques), under the supervision of teaching staff.

4. Individual tutorials: Personalised sessions, by appointment, to address queries and monitor the student’s learning progress.

5. Exams: Assessment tests covering theoretical content (mid-term exam and final exam) and laboratory practicals.

6. Independent study: Study of theoretical and practical content, completion of additional exercises and consultation of the recommended reading list.

N10201

Morphology, Structure and Function of Organs and Systems II

Código: N10201 Imprimir

Year 1. Annual module. Foundation course. 12 credits.

Profesores

Antonio Adeba Garcia	Ver biodata Senior Registrar in Cardiology at Cabueñes University Hospital (Gijón), working within the Heart Failure Unit, having completed his MIR training at the Central University Hospital of Asturias between 2016 and 2021. Doctor of Medicine Cum Laude from the University of Oviedo with the thesis ‘Medium-term outcomes of functional mitral regurgitation treated by percutaneous repair with valve clipping’. Certification in Heart Failure from the Heart Failure Association of the European Society of Cardiology (2024), Master’s degrees in Advances in Cardiology, Clinical Cardiology and Clinical Medicine, and postgraduate training in health statistics, coronary heart disease and thromboembolic disease. Scientific output comprising 15 articles indexed in PubMed, over 50 posters and conference presentations (at least 30 of which as first author) and 4 book chapters. Member of the Official College of Physicians of Asturias, the Spanish Society of Cardiology and the European Society of Cardiology.
Alberto Alperi García	Ver biodata University Education: Bachelor’s degree in Medicine from the University of Oviedo. PhD from the Health Sciences Programme at the University of Oviedo in 2020. Master’s degree in Research Methodology in Health Sciences (2016–2021, Autonomous University of Barcelona) Master’s degree in the management of structural heart disease (2018–2020, Francisco de Viloria University). Master’s degree in Acute Cardiac Care (2017–2019, Menéndez Pelayo International University). Master’s degree in Diagnostic Imaging in Cardiology (2019–2021, San Antonio Catholic University). Master’s Degree in Advances in Cardiology (2023–2025, San Antonio Catholic University). Professional History: Specialisation in Cardiology as a Junior Registrar at the Central University Hospital of Asturias (2013–2018). Sub-specialisation in interventional coronary and structural cardiology at the Quebec Heart Institute (Canada) (2018–2021). Consultant Cardiologist at the Central University Hospital of Asturias (2021–present).
Belén Alonso Estanillo - Coordinador	Ver biodata Bachelor’s degree in Molecular Biology. PhD in Biology and Biochemistry. Her areas of expertise are Biochemistry and Genetics. She has 12 years’ teaching experience, during which she has taught the following subjects: Biochemistry, Genetics, Physiology and Biology. She has 17 years’ professional experience. Her professional experience includes: research into the biology of cetaceans and primates. Lecturer at a university college and a university. Veterinary laboratory technician (ATV) at a veterinary hospital.
Eduardo Higueras Mora	Ver biodata A doctor qualified from the University of Alcalá. A specialist in Clinical Biochemistry and Pathological Anatomy, trained at the Central University Hospital of Asturias (HUCA). He has specific training and experience in Molecular Pathology, including specialised rotations in this field. He currently works as a Specialist in Pathological Anatomy at Cabueñes University Hospital, where he is in charge of Gastrointestinal Pathology.
Natalia Fontanil Vior	Ver biodata Graduated in Medicine from the Faculty of Oviedo in 2019 Specialist in Pathology at the Asturias Medical Centre since 2024 Junior Registrar in Pathology at the Marqués de Valdecilla Hospital from 25 September 2020 to 24 September 2024 Master’s degree in continuing professional development in oncological pathology in 2025
Marcos Manuel García Guimaraes	Ver biodata Graduated in Medicine from the Faculty of Oviedo in 2019 Specialist in Pathology at the Asturias Medical Centre since 2024 Junior Registrar in Pathology at the Marqués de Valdecilla Hospital from 25 September 2020 to 24 September 2024 Master’s degree in continuing professional development in oncological pathology in 2025
Paula Antuña Álvarez	Ver biodata Graduated in Medicine from the Faculty of Oviedo in 2019 Specialist in Pathology at the Asturias Medical Centre since 2024 Junior Registrar in Pathology at the Marqués de Valdecilla Hospital from 25 September 2020 to 24 September 2024 Master’s degree in continuing professional development in oncological pathology in 2025
Luis Matesanz Garcia	Ver biodata European Doctorate in Health Sciences and Biomedicine from Rey Juan Carlos University, where he was awarded the grade of Distinction Cum Laude, the Extraordinary Doctoral Award and various honours for his thesis on entrapment neuropathies and neuropathic pain. His research focuses on the pathophysiology of peripheral neuropathic pain, the identification of biomarkers, the mechanisms of sensitisation and the development of personalised treatments through therapeutic exercise and other conservative interventions. She has an outstanding record of scientific publications in high-impact international journals such as PAIN, The Journal of Pain, Journal of Neuroimmunology or Neuromodulation,Musculoskeletal Science and Practice. Furthermore, he participates in established research groups, competitive projects and the supervision of doctoral theses relating to pain and peripheral neuropathies. At an international level, he undertook a three-month research placement at the University of Oxford (Nuffield Department of Clinical Neurosciences) and was a visiting lecturer at the University of Ljubljana (Slovenia), where he delivered the seminar Assessment and Treatment of Peripheral Nerve Disorders and established new scientific collaborations. He has also taken part in international teaching initiatives with the Autonomous University of Manizales (Colombia) on the assessment and treatment of peripheral nerve disorders. has delivered over 1,000 hours of teaching at undergraduate and postgraduate level in the fields of physiotherapy, pharmacology, therapeutic exercise and pain, as well as supervising final-year dissertations and co-supervising doctoral theses. She has been awarded the Juan Antonio Micó Prize for the Best Doctoral Thesis on Pain and the Prize for the Best Doctoral Thesis from the Madrid Professional Association of Physiotherapists
Diego Pérez Díez	Ver biodata Bachelor of Medicine and Surgery from the University of Zaragoza, class of 1996–2002 (average mark: 3.38. 13 First-Class Honours, 18 Distinctions, 1 Upper Second) - Postgraduate studies, Diploma of Advanced Studies (DEA) with a grade of ‘Outstanding’ from the University of A Coruña, 2005–2007. - Master’s degree in Clinical Electrophysiology and Cardiac Pacing from the Faculty of Medicine, University of Barcelona, 2008–2010 (30 credits). - Diploma in Design and Statistics in Health Sciences (30 ECTS): Autonomous University of Barcelona. - Accreditation in Interventional Cardiac Pacing (European Heart Rhythm Association) obtained at the Europace Congress (Berlin, June 2009). - Accreditation in Invasive Electrophysiology (European Heart Rhythm Association) obtained at Cardiostim (Nice, June 2010). - Master’s Degree in Cardiac Electrophysiology and Therapeutics. CEU San Pablo University, 2011–2013. (60 ECTS credits). - Master’s in Cardiology (Miguel Hernández University, Spanish Society of Cardiology, Menarini), 2011–2012. (60 credits). Coordinator of the Arrhythmia Unit within the Cardiology Department at Cabueñes University Hospital, Gijón, Asturias, from 20 October 2023 to the present. - Specialist course in atrial fibrillation (30 credits). 2013–2014. University of Santiago de Compostela. - University Expert in the diagnosis and treatment of heart failure and coronary heart disease. 2021. San Antonio Catholic University. 25.5 credits (ECTS). - Excellence in Hospital Management: Towards Value in Healthcare. ESADE. 42 teaching hours. 21 November 2024 to 20 June 2025. Madrid.
Cristina Magadán Álvarez	Ver biodata Bachelor of Medicine from the University of Cantabria (2007–2013), including an Erasmus placement at Ghent University (Belgium). Completed her MIR training in General and Gastrointestinal Surgery at the Marqués de Valdecilla University Hospital (2014–2019), including a placement as an International Research Fellow at NYU Winthrop Hospital (2017). Senior Registrar (FEA) in General and Gastrointestinal Surgery at San Agustín University Hospital (Avilés) since 2019. PhD from the University of Cantabria (2023), with a thesis on short- and long-term survival in hepatocellular carcinoma treated by resection or liver transplantation. Master’s degree in Breast Surgery from the University of Barcelona (2023). Author and co-author of publications in national and international scientific journals, including Annals of Surgery, British Journal of Surgery and Cirugía Española. Lecturer at San Agustín University Hospital and honorary lecturer at the University of Oviedo since 2019. Master’s degree in Teaching from Alfonso X el Sabio University (2026). Undergraduate Programme Coordinator in Medicine at the Alfonso X Asturias University Centre.
José Alberto Medina Villanueva	Ver biodata Bachelor of Medicine from the University of Cantabria (2007–2013), including an Erasmus placement at Ghent University (Belgium). Completed her MIR training in General and Gastrointestinal Surgery at the Marqués de Valdecilla University Hospital (2014–2019), including a placement as an International Research Fellow at NYU Winthrop Hospital (2017). Senior Registrar (FEA) in General and Gastrointestinal Surgery at San Agustín University Hospital (Avilés) since 2019. PhD from the University of Cantabria (2023), with a thesis on short- and long-term survival in hepatocellular carcinoma treated by resection or liver transplantation. Master’s degree in Breast Surgery from the University of Barcelona (2023). Author and co-author of publications in national and international scientific journals, including Annals of Surgery, British Journal of Surgery and Cirugía Española. Lecturer at San Agustín University Hospital and honorary lecturer at the University of Oviedo since 2019. Master’s degree in Teaching from Alfonso X el Sabio University (2026). Undergraduate Programme Coordinator in Medicine at the Alfonso X Asturias University Centre.
José Ramón Méndez Álvarez	Ver biodata Bachelor of Medicine from the University of Cantabria (2007–2013), including an Erasmus placement at Ghent University (Belgium). Completed her MIR training in General and Gastrointestinal Surgery at the Marqués de Valdecilla University Hospital (2014–2019), including a placement as an International Research Fellow at NYU Winthrop Hospital (2017). Senior Registrar (FEA) in General and Gastrointestinal Surgery at San Agustín University Hospital (Avilés) since 2019. PhD from the University of Cantabria (2023), with a thesis on short- and long-term survival in hepatocellular carcinoma treated by resection or liver transplantation. Master’s degree in Breast Surgery from the University of Barcelona (2023). Author and co-author of publications in national and international scientific journals, including Annals of Surgery, British Journal of Surgery and Cirugía Española. Lecturer at San Agustín University Hospital and honorary lecturer at the University of Oviedo since 2019. Master’s degree in Teaching from Alfonso X el Sabio University (2026). Undergraduate Programme Coordinator in Medicine at the Alfonso X Asturias University Centre.
Beatriz Ordóñez Fernández	Ver biodata Bachelor of Medicine from the University of Cantabria (2007–2013), including an Erasmus placement at Ghent University (Belgium). Completed her MIR training in General and Gastrointestinal Surgery at the Marqués de Valdecilla University Hospital (2014–2019), including a placement as an International Research Fellow at NYU Winthrop Hospital (2017). Senior Registrar (FEA) in General and Gastrointestinal Surgery at San Agustín University Hospital (Avilés) since 2019. PhD from the University of Cantabria (2023), with a thesis on short- and long-term survival in hepatocellular carcinoma treated by resection or liver transplantation. Master’s degree in Breast Surgery from the University of Barcelona (2023). Author and co-author of publications in national and international scientific journals, including Annals of Surgery, British Journal of Surgery and Cirugía Española. Lecturer at San Agustín University Hospital and honorary lecturer at the University of Oviedo since 2019. Master’s degree in Teaching from Alfonso X el Sabio University (2026). Undergraduate Programme Coordinator in Medicine at the Alfonso X Asturias University Centre.
Verónica Robles Marinas	Ver biodata Bachelor of Medicine from the University of Cantabria (2007–2013), including an Erasmus placement at Ghent University (Belgium). Completed her MIR training in General and Gastrointestinal Surgery at the Marqués de Valdecilla University Hospital (2014–2019), including a placement as an International Research Fellow at NYU Winthrop Hospital (2017). Senior Registrar (FEA) in General and Gastrointestinal Surgery at San Agustín University Hospital (Avilés) since 2019. PhD from the University of Cantabria (2023), with a thesis on short- and long-term survival in hepatocellular carcinoma treated by resection or liver transplantation. Master’s degree in Breast Surgery from the University of Barcelona (2023). Author and co-author of publications in national and international scientific journals, including Annals of Surgery, British Journal of Surgery and Cirugía Española. Lecturer at San Agustín University Hospital and honorary lecturer at the University of Oviedo since 2019. Master’s degree in Teaching from Alfonso X el Sabio University (2026). Undergraduate Programme Coordinator in Medicine at the Alfonso X Asturias University Centre.
Leonor Meana Carballo	Ver biodata Bachelor of Medicine from the University of Cantabria (2007–2013), including an Erasmus placement at Ghent University (Belgium). Completed her MIR training in General and Gastrointestinal Surgery at the Marqués de Valdecilla University Hospital (2014–2019), including a placement as an International Research Fellow at NYU Winthrop Hospital (2017). Senior Registrar (FEA) in General and Gastrointestinal Surgery at San Agustín University Hospital (Avilés) since 2019. PhD from the University of Cantabria (2023), with a thesis on short- and long-term survival in hepatocellular carcinoma treated by resection or liver transplantation. Master’s degree in Breast Surgery from the University of Barcelona (2023). Author and co-author of publications in national and international scientific journals, including Annals of Surgery, British Journal of Surgery and Cirugía Española. Lecturer at San Agustín University Hospital and honorary lecturer at the University of Oviedo since 2019. Master’s degree in Teaching from Alfonso X el Sabio University (2026). Undergraduate Programme Coordinator in Medicine at the Alfonso X Asturias University Centre.
Marta María Sánchez Menéndez	Ver biodata Bachelor of Medicine, Doctor of Medicine, University of Oviedo. Grade: First Class with Distinction (Cum Laude) Specialist in Rheumatology (MIR). F.E.A. Rheumatology, HUCA, 2009–2010. Junior Specialist in Rheumatology at the Asturias Medical Centre Hospital Postgraduate courses at the University of Oviedo. Department of Surgery and Medical-Surgical Specialities. Grade: First Class SER Master’s in Immune-Mediated Rheumatic Diseases. Rey Juan Carlos University Specialisation course in Osteoporosis and Metabolic Bone Diseases and in Pain Management. Open University of Catalonia Advanced level in Musculoskeletal Ultrasound. SER School of Ultrasound Visiting Lecturer. Department of Medicine and Health Sciences, University of Oviedo (2006–2008) Lecturer at the Padre Ossó Faculty, a centre affiliated with the University of Oviedo (2022–2026). Courses taught on the Bachelor’s Degree in Occupational Therapy: Human Anatomy I, Human Anatomy II, Geriatrics and Osteoarticular Pathologies. Academic coordinator for the modules Geriatrics and Osteoarticular Disorders (2025–2026) and Human Anatomy I (2022–2023) Research Trainee, Department of Rheumatology. Mayo Clinic, Rochester, Minnesota, USA (2010) PUBLICATIONS Arias-Guillén M, Sánchez Menéndez MM. High rates of tuberculin skin test positivity due to methotrexate therapy: False-positive results? Seminars in Arthritis and Rheumatism. 2018;48(3):538–546. doi:10.1016/j.semarthrit.2018.03.018. PMID: 2973517 ¿ Ernst FC, Sánchez-Menéndez M, et al. Cardiovascular risk profile at the onset of psoriatic arthritis: a population-based cohort study. Arthritis Care & Research (Hoboken). 2015;67(7):1015–1021 doi: 10.1002/acr.22536. PMID: 25581120. ¿ Cartin-Ceba R, Golbin JM, Keogh KA, Peikert T, Sánchez-Menéndez M, et al. Rituximab for remission induction and maintenance in refractory granulomatosis with polyangiitis (Wegener’s): a single-centre ten-year experience. Arthritis & Rheumatism. June 2012; 64(6):3770–3778. doi: 10.1002/art.34584. PMID: 2273002821. doi: 10.1002/art.34584.
José Miguel Vegas Valle	Ver biodata Dr José Miguel Vegas (Salamanca, 1977) is a cardiologist accredited by the SEC in haemodynamics and interventional cardiology, with a strong track record in clinical practice, research and innovation. He holds a degree in Medicine from the University of Salamanca (2001) and a PhD from the University of Oviedo (2019), and completed his residency in Cardiology at HUCA and a fellowship at St George’s University of London. He works as a Senior Consultant in the Cardiology Department at Cabueñes University Hospital (Gijón), where he also supervises residents. His training is notable for its focus on artificial intelligence and health data analysis, with postgraduate courses at MIT Sloan, Harvard and the UAB, as well as master’s degrees in Clinical Cardiology, Acute Cardiovascular Conditions and Clinical Unit Management. In the scientific sphere, he has over 60 publications in high-impact journals such as the NEJM, JACC and the European Heart Journal, focusing on coronary intervention, antiplatelet therapy, acute coronary syndrome and undiagnosed diabetes, and has presented some 200 papers at national and international conferences. In the field of innovation and research, he integrates cardiology with artificial intelligence: as Principal Investigator (PI), he leads an AI-based tool for cardiac amyloidosis (ISPA), the Calc-IAsturias project for the detection of coronary calcium via CT (Ministry of Health) and the AYUDHA platform for remote cardiac rehabilitation (Gijón City Council). He sits on evaluation and research committees and has received several awards, including one from the SEC for best article (2010) and the 1st Innovation Award from the Royal Academy of Medicine of the Principality of Asturias.
María del Carmen Sánchez Blanco	Ver biodata Specialist in Gynaecology and Obstetrics Official Doctorate from the Doctoral Programme in Molecular and Cellular Biology at the University of Oviedo Lecturer at the Asturias MIR Academy Associate Lecturer at the University of Oviedo Master’s degree in Perinatal Diagnosis (2026) Master’s degree in Minimally Invasive Surgery Expert in the ultrasound diagnosis of endometrial pathology. Expert in the ultrasound diagnosis of ovarian pathology. Recent publications: Sánchez Blanco C, García Cancelo M, González Martínez C, Cardo González L, Diéguez Felechosa M. Current status of iodine intake in pregnant women in Asturias, Spain. Endocrinol Diabetes Nutr (Engl Ed). Dec 2025;72(10):501646. doi: 10.1016/j.endien.2025.501646. Epub 15 Oct 2025. PMID: 41102067. Martínez-Morillo E., Álvarez Rodríguez S., Muñoz Peña S., Sánchez Blanco C., Jiménez Mendiguchia L., Corte Arboleya Z., & Venta Obaya R. (2026). Comparison of Two Mathematical Models for the Screening of Pre-eclampsia Using Free Cloud Computing Resources. Applied Medical Informatics, 48(2), 58–66. - 66
Juan José Rondán Murillo	Ver biodata Doctor of Medicine from the University of Oviedo and a specialist in cardiology. I currently practise in the Cardiology Department at the Central University Hospital of Asturias (HUCA). I have over 20 years’ clinical experience, focusing mainly on interventional cardiology and the prevention of cardiovascular risk. My career has been complemented by extensive postgraduate training in cardiology, clinical management and research. I combine my clinical work with teaching, contributing to the training of undergraduates, junior doctors and healthcare professionals through various university and specialist training programmes. In the field of research, I am a member of the ISPA Cardiac Pathology Research Group and have participated as principal investigator and co-investigator in numerous national and international multicentre clinical trials. I am the author of more than 60 scientific publications and several book chapters, and I remain firmly committed to excellence in patient care, research and the training of professionals capable of meeting the challenges of modern cardiovascular medicine.
Rafael Rosillo Camblor	Ver biodata University Professor. PhD in Business Administration. Computer Engineer. Principal Investigator on European and regional projects. Several publications in high-impact journals listed in the JCR. Two six-year periods of research and three five-year periods of teaching. Principal Investigator on a knowledge transfer project.
José Rozado Castaño	Ver biodata University Professor. PhD in Business Administration. Computer Engineer. Principal Investigator on European and regional projects. Several publications in high-impact journals listed in the JCR. Two six-year periods of research and three five-year periods of teaching. Principal Investigator on a knowledge transfer project.
Ruth Salmón Maroto	Ver biodata University Professor. PhD in Business Administration. Computer Engineer. Principal Investigator on European and regional projects. Several publications in high-impact journals listed in the JCR. Two six-year periods of research and three five-year periods of teaching. Principal Investigator on a knowledge transfer project.

N10202

Biology

Código: N10202 Imprimir

Year 1. Annual module. Foundation course. 6 credits.

Profesores

Belén Alonso Estanillo	Ver biodata Bachelor’s degree in Molecular Biology. PhD in Biology and Biochemistry. Her areas of expertise are Biochemistry and Genetics. She has 12 years’ teaching experience, during which she has taught the following subjects: Biochemistry, Genetics, Physiology and Biology. She has 17 years’ professional experience. Her professional experience includes: research into the biology of cetaceans and primates. Lecturer at a university college and a university. Veterinary laboratory technician (ATV) at a veterinary hospital.
Sarah Panera Martínez	Ver biodata I hold a degree in Biology from the University of León, a Master’s degree in Plant Biotechnology (University of Oviedo), a Master’s degree in Biostatistics and Bioinformatics (Open University of Catalonia), in Teacher Training (International University of La Rioja) and hold a PhD in Veterinary and Food Sciences from the University of León. I hold accreditation as an Assistant Lecturer from the ACSUCY, having accumulated more than 450 hours of teaching experience at the University of León and the International University of La Rioja.
David Carballo Beltrán	Ver biodata I hold a degree in Biology from the University of León, a Master’s degree in Plant Biotechnology (University of Oviedo), a Master’s degree in Biostatistics and Bioinformatics (Open University of Catalonia), in Teacher Training (International University of La Rioja) and hold a PhD in Veterinary and Food Sciences from the University of León. I hold accreditation as an Assistant Lecturer from the ACSUCY, having accumulated more than 450 hours of teaching experience at the University of León and the International University of La Rioja.
Mario García Domínguez - Coordinador	Ver biodata I hold a degree in Biology from the University of León, a Master’s degree in Plant Biotechnology (University of Oviedo), a Master’s degree in Biostatistics and Bioinformatics (Open University of Catalonia), in Teacher Training (International University of La Rioja) and hold a PhD in Veterinary and Food Sciences from the University of León. I hold accreditation as an Assistant Lecturer from the ACSUCY, having accumulated more than 450 hours of teaching experience at the University of León and the International University of La Rioja.
Paula Díaz Bulnes	Ver biodata I hold a degree in Biology from the University of León, a Master’s degree in Plant Biotechnology (University of Oviedo), a Master’s degree in Biostatistics and Bioinformatics (Open University of Catalonia), in Teacher Training (International University of La Rioja) and hold a PhD in Veterinary and Food Sciences from the University of León. I hold accreditation as an Assistant Lecturer from the ACSUCY, having accumulated more than 450 hours of teaching experience at the University of León and the International University of La Rioja.
Beatriz Trigal Triguero	Ver biodata I hold a degree in Biology from the University of León, a Master’s degree in Plant Biotechnology (University of Oviedo), a Master’s degree in Biostatistics and Bioinformatics (Open University of Catalonia), in Teacher Training (International University of La Rioja) and hold a PhD in Veterinary and Food Sciences from the University of León. I hold accreditation as an Assistant Lecturer from the ACSUCY, having accumulated more than 450 hours of teaching experience at the University of León and the International University of La Rioja.

Objectives

1. To provide students with a foundation in cell biology and molecular biology, and in particular in biomedical reasoning, enabling them to gain a better understanding of the various biological aspects of their degree programme.

2. To equip students with a basic knowledge of those topics that will be key in the future for the application of new diagnostic and treatment methods in medicine.

3. To use appropriate scientific terminology and biomedical reasoning, thereby enabling a better understanding of the various aspects of health sciences.

4. To be able to solve problems and make judgements within a field of study, by gathering and interpreting relevant data in accordance with the scientific method.

5. To recognise and explain the main functional characteristics of the organelles of the eukaryotic cell, as well as the mechanisms regulating intracellular processes.

6. To understand the cellular and molecular basis of tissue organisation, differentiation, regeneration and repair, as well as the mechanisms involved in cell-cell interactions.

7. Understand and be able to carry out the basic experimental techniques used in a cell and molecular biology laboratory.

8. To acquire a basic understanding of molecular evolution and its application in medicine.

9. Develop teamwork skills.

10. Be able to conduct effective literature searches and use the main health sciences databases.

Prerequisites

Prior knowledge of organic and inorganic chemistry and biology is required. Students must have a firm grasp of the basic concepts of: atomic structure and molecular bonding, chemical formulae and units, the concept of chemical equilibrium, the concept of pH and weak acids and their conjugate bases, the concept of polar and non-polar molecules, types of weak interactions, and the concept of oxidation-reduction.

Competencies

Not applicable.

Learning outcomes

RK1. Understanding cell structure and function.

RK2. Cell communication.

RK3. Excitable membranes.

RK4. The cell cycle.

RK5. Cell differentiation and proliferation.

RK23. Growth, maturation and ageing of the various organ systems.

RS17. Be able to interpret the results of laboratory diagnostic tests.

Description of the content

Core subject covering the compulsory core content of Biology: ecology and evolution, cytology, histology and embryology.

KNOWLEDGE:

1. General concepts of biology. Ecology and evolution.

2. General structure of the cell. Extracellular matrix.

3. Biomolecules. Characteristics and properties. Organisation and general structure of cellular metabolism.

4. Cell membrane. Transport systems. Excitable membranes.

5. Cytoplasmic structures. Cytoskeleton.

6. Exocytosis. Endocytosis.

7. Signal transduction systems.

8. Cell cycle. Control systems.

9. Ageing and cell death.

10. Mechanisms of cell differentiation and proliferation. Maintenance of genetic information.

11. Partial utilisation of genetic information. Reversibility of differentiation. Stem cells.

12. Carry out and recognise basic morphological staining techniques in the laboratory.

13. Operate an optical microscope and use it to identify different cell types and their basic structural components.

14. Recognise and interpret, using an optical microscope, the different phases of mitosis in rapidly renewing cells and tissues.

15. Recognise and interpret, using an optical microscope, cells in culture and their patterns of in vitro growth.

16. Recognise and interpret, at the ultrastructural level, the cell membrane, organelles and components of the cytoskeleton.

17. Structural and functional organisation of the main tissues in the human body.

18. Levels of organisation and molecular and cellular function.

19. Structure, distribution and function of epithelial, connective, muscular and nervous tissues.

20. Tissue degeneration, repair and regeneration.

21. Tissue ageing.

22. Tissue engineering.

SKILLS:

1. Carry out and recognise basic morphological stains in the laboratory.

2. Operate an optical microscope and use it to identify different cell types and their basic structural components.

3. Recognise and interpret, using an optical microscope, cells in culture and their patterns of in vitro growth.

4. Recognise and interpret, at the ultrastructural level, the cell membrane, organelles and components of the cytoskeleton.

5. Recognise the structure of human tissues using macroscopic and microscopic methods and imaging techniques.

6. To practise, under supervision, techniques for the fixation and preservation of biological samples.

Training activities

1. Lectures: Explanation of the theoretical foundations of cell biology, histology and embryology, using IT tools and audiovisual resources. 30 hours (30 face-to-face).

3. Laboratory practicals: Use of the optical microscope, staining techniques and identification of cellular and tissue structures, under the supervision of teaching staff. 15 hours (15 face-to-face).

4. Individual tutorials: Personalised sessions, by appointment, to address queries and monitor the student’s learning progress. 1 hour (1 face-to-face session).

5. Examinations: Tests to assess theoretical content and laboratory practicals. 4 hours (4 face-to-face).

6. Independent study: Study of theoretical and practical content, completion of additional exercises and consultation of the recommended reading list. 85 hours (0 face-to-face).

Total: 150 hours (65 face-to-face).

Assessment system and criteria

SE1: Objective assessment by teaching staff via the final course examination and a mid-term examination: 75%

SE2: Assessment of the student’s attendance and participation in class: 5%

SE3: Assessment of laboratory practicals via a practicals examination: 10%

SE4: Assessment of individual and/or group assignments through submission and/or presentation of work: 10%

TOTAL:

FIRST FOUR-MONTH PERIOD

Code

Subjects

Character*

ECTS

N10203

Biochemistry I

Código: N10203 Imprimir

Course 1: First-term module. Basic training. 6 credits.

Profesores

Maria Dolores Chiara Romero	Ver biodata A doctor of medicine and holder of a PhD from the University of Seville, with postdoctoral training at Harvard Medical School, where he contributed to elucidating the mechanisms of pre-mRNA splicing and to identifying components of the spliceosome. On his return to Spain, he investigated the diversity of ion channels and, as a Miguel Servet Research Fellow at the Virgen del Rocío Hospital, identified HIF as a regulator of ion channel genes and characterised T-type calcium channels in hypoxia-induced excitability. Since 2002, he has been a Full Professor at the University of Seville (currently on voluntary leave of absence) and, subsequently, a Miguel Servet Research Fellow at the Central Hospital of Asturias (Oviedo), where he leads the Rare Tumours Group (Health Research Institute of the Principality of Asturias – ISPA / University Institute of Oncology of the Principality of Asturias – IUOPA). His research focuses on the molecular mechanisms of cancer progression, the tumour microenvironment, and tumours driven by hypoxia and mutations in mitochondrial complex II genes. Key indicators: over 70 publications, H-index = 24, 2,134 citations, 5 recognised six-year research periods, 13 doctoral theses supervised (Cum Laude) and 5 patents.
Belén Alonso Estanillo - Coordinador	Ver biodata Bachelor’s degree in molecular biology. PhD in biology and biochemistry. Her areas of expertise are biochemistry and genetics. She has 12 years’ teaching experience, during which she has taught the following subjects: biochemistry, genetics, physiology and biology. She has 17 years’ professional experience. Her professional experience includes: research into the biology of cetaceans and primates. Lecturer at a university college and a university. Veterinary laboratory technician (ATV) at a veterinary hospital.
Francisco Javier Cepeda Piorno	Ver biodata Bachelor’s degree in molecular biology. PhD in biology and biochemistry. Her areas of expertise are biochemistry and genetics. She has 12 years’ teaching experience, during which she has taught the following subjects: biochemistry, genetics, physiology and biology. She has 17 years’ professional experience. Her professional experience includes: research into the biology of cetaceans and primates. Lecturer at a university college and a university. Veterinary laboratory technician (ATV) at a veterinary hospital.
Mario García Domínguez	Ver biodata Bachelor’s degree in molecular biology. PhD in biology and biochemistry. Her areas of expertise are biochemistry and genetics. She has 12 years’ teaching experience, during which she has taught the following subjects: biochemistry, genetics, physiology and biology. She has 17 years’ professional experience. Her professional experience includes: research into the biology of cetaceans and primates. Lecturer at a university college and a university. Veterinary laboratory technician (ATV) at a veterinary hospital.
David Carballo Beltrán	Ver biodata Bachelor’s degree in molecular biology. PhD in biology and biochemistry. Her areas of expertise are biochemistry and genetics. She has 12 years’ teaching experience, during which she has taught the following subjects: biochemistry, genetics, physiology and biology. She has 17 years’ professional experience. Her professional experience includes: research into the biology of cetaceans and primates. Lecturer at a university college and a university. Veterinary laboratory technician (ATV) at a veterinary hospital.
Beatriz Trigal Triguero	Ver biodata Bachelor’s degree in molecular biology. PhD in biology and biochemistry. Her areas of expertise are biochemistry and genetics. She has 12 years’ teaching experience, during which she has taught the following subjects: biochemistry, genetics, physiology and biology. She has 17 years’ professional experience. Her professional experience includes: research into the biology of cetaceans and primates. Lecturer at a university college and a university. Veterinary laboratory technician (ATV) at a veterinary hospital.

Objectives

˗ To understand the general principles of biochemistry, identify the main structural characteristics of biomolecules and deduce the functions they perform in the body, in metabolism and in the transmission of information.

˗ To identify key molecules in biochemical processes (carbohydrates, lipids and proteins), apply the mechanisms of enzymatic regulation and relate them to associated diseases.

˗ To explain the mechanisms of interaction between the main molecules and biomolecules.

˗ Carry out basic experimental techniques used in a biochemistry and molecular biology laboratory.

Prerequisites

Recommended prior knowledge of organic and inorganic chemistry and biology: pH, acid-base balance, buffer solutions, bonds between organic molecules and atomic structure.

Competencies

Not applicable.

Learning outcomes

Knowledge and content:

˗ RK6 – Biomolecules.

Skills and competences:

˗ RS17 – Knowing how to interpret the results of laboratory diagnostic tests.

Description of the content

Core subject in which compulsory core content in molecular biology and biochemistry is taught:

KNOW:

- Biomolecules. Characteristics and properties. General organisation and structure of cellular metabolism.

- Physico-chemical properties of water and their biological significance.

- Amino acids. Structure and function of proteins.

- Enzymology.

- Thermodynamics. Biological energy transfer processes.

- RNA and DNA structures. Types and biological functions.

SKILLS:

- Handling of materials and basic laboratory techniques.

- Determining glucose levels in different types of samples. Interpreting a profile.

- Practising, under supervision, the main quantitative techniques: colorimetry and fluorimetry.

- Practising, under supervision, the main techniques for the separation and quantification of proteins.

Contents:

Unit 1. Introduction to Biochemistry: general principles

Unit 2. Biomolecules: water and its biological significance. Carbohydrates

Unit 3. Biomolecules: lipids

Unit 4. Amino acids: structure and classification

Unit 5. Proteins: structure and function

Unit 6. Enzymology: catalytic proteins

Unit 7. Enzymology: reaction kinetics

Unit 8. Enzymology: inhibition and regulation of reactions

UD9. Bioenergetics: biological energy transfer processes

Unit 10. Nucleic acids: structure of DNA and RNA, types and biological functions

Learning activities

1. Lectures: Explanation of the theoretical foundations of structural biochemistry (biomolecules, amino acids, proteins, enzymology, thermodynamics and nucleic acids), using computer tools and audiovisual resources. 30 hours (30 face-to-face).

3. Laboratory practicals: Carrying out basic experimental techniques in biochemistry and molecular biology under the supervision of teaching staff. 15 hours (15 face-to-face).

4. Individual tutorials: Personalised sessions, by appointment, to address queries and monitor the student’s learning progress. 1 hour (1 face-to-face session).

5. Exams: Assessments of theoretical content and laboratory practicals. Exams: 4 hours (4 face-to-face).

6. Independent study: Study of theoretical and practical content, completion of additional exercises and consultation of the recommended reading list. 90 hours (0 face-to-face).

Total: 150 hours (60 face-to-face).

Assessment system and criteria

SE1: Objective assessment by teaching staff through examinations: 75%

SE2: Assessment of student attendance and class participation based on attendance and group work presentations: 10%

SE3: Assessment of laboratory practicals via a practicals examination: 15%

Timetable

Click on this link to view the detailed timetable in Excel

Session	Activity	Description	Assessment
1	MG	Course introduction
2	MG	Topic 1: General principles
3	MG	Topic 2: Carbohydrates: energy and fibre (1/2)
4	MG	Topic 2: Carbohydrates: energy and fibre (2/2)
5	MG	Revision
6	MG	Topic 3: Lipids: energy and structure (1/2)
7	MG	Topic 3: Lipids: energy and structure (2/2)
8	SM	Exercises I – Introduction
9	MG	Revision
10	MG	Topic 4: Amino acids: they form proteins (1/2)
11	MG	Topic 4: Amino acids: they form proteins (2/2)
12	SM	Exercises II – carbohydrates
13	MG	Revision
14	MG	Mid-term exam covering amino acids.
15	MG	Topic 5: Proteins: each with its own function (1/2)
16	SM	Exercises III – carbohydrates – lipids
17	MG	Topic 5: Proteins: each with its own function (2/2)
18	MG	Revision
19	SM	Exercises IV – lipids
20	MG	Topic 6: Enzymology: catalytic proteins (1/2)
21	MG	Topic 6: Enzymology: catalytic proteins (2/2)
22	MG	Revision
23	MG	Topic 6: Enzymology: reaction rates or kinetics (1/2)
24	SM	Exercises V – amino acids + proteins
25	LB	Isolation of casein from milk, quantitative analysis and protein electrophoresis.
26	LB	Quantification of milk proteins. Bradford method. Separation of pigments by thin-layer chromatography (TLC).
27	LB	Identification of carbohydrates. Protein electrophoresis.
28	MG	Topic 7: Enzymology: reaction rates or kinetics (2/2)
29	SM	Exercises VI – amino acids + proteins
30	LB	Analysis of protein electrophoresis results. Effect of various factors on the activity of the enzyme amylase
31	MG	Revision
32	LB	Questions and assessment of laboratory practicals (practical exam)
33	MG	Topic 8: Enzymology: inhibition and regulation of reactions (1/2)
34	MG	Topic 8: Enzymology: inhibition and regulation of reactions (2/2)
35	SM	Exercises VII – Enzymology
36	MG	Revision
37	MG	Review
38	MG	Topic 9 Bioenergetics: The Energy of our Molecules
39	MG	Topic 10: Nucleic acids.
40	MG	Presentation of oral assignments
41	MG	Oral presentations
42	SM	Exercises VIII – Bioenergetics
43	MG	Presentation of oral assignments
44	SM	Exercises IX – Oral presentations
45	SM	Oral presentations (assessment of attendance and participation through group presentations)
46	CN	Tutorial to monitor the learning process (date to be confirmed, at the student’s request)
47	EV	Final examination for the module (official date as per the examination timetable; not included in the teaching plan)

Bibliography

Essential:

1. Lehninger, Albert L.; Nelson, David L.; Cox, Michael M.; Cuchillo Foix, Claudi M.

Principles of Biochemistry

5th ed. Omega. 2009.

ISBN: 9788428214865

2. Meisenberg, Gerhard; Simmons, William H.

Principles of Medical Biochemistry

4th ed. Elsevier. 2018.

ISBN: 978-84-9113-3

https://sapiens.uax.com/discovery/fulldisplay?docid=alma99598890303591&context=L&vid=34UAX_INST:34UAX_V1&lang=es&search_scope=MyInst_and_CI&adaptor=Local%20Search%20Engine&tab=Everything&query=any,contains,Principles%20of%20Biochemistry&sortby=date_d&facet=frbrgroupid,include,9013531213894733749&offset=0

N10204

Statistics

Código: N10204 Imprimir

Course 1: First-term module. Foundation course. 7 credits.

Profesores

Jaime de Algorta de Pineda	Ver biodata Doctor of Medicine (1993, New stimuli for growth hormone secretion. Supervisor: Prof. Dr Pedro Martul Tobio), accredited by ANECA and UNIQAL, EuCP-certified pharmacologist, with 30 years’ professional experience divided between clinical medicine (Col. 334806789) and clinical research across all its fields: as principal investigator of clinical trials in hospital settings, as a sponsor within the pharmaceutical industry, and as a clinical development consultant for research firms and scientific and regulatory consultancy firms. All of the above has been combined with academic and teaching activities at various universities and educational institutions.
Sarah Panera Martínez - Coordinador	Ver biodata I hold a degree in Biology from the University of León, a Master’s degree in Plant Biotechnology (University of Oviedo), and Master’s degrees in Biostatistics and Bioinformatics (Open University of Catalonia), in Teacher Training (International University of La Rioja) and hold a PhD in Veterinary and Food Sciences from the University of León. I hold accreditation as an Assistant Lecturer from the ACSUCY, having accumulated more than 450 hours of teaching experience at the University of León and the International University of La Rioja.
Marina Jimenez Muñoz	Ver biodata PhD in Statistics with experience in teaching, consultancy and interdisciplinary research. Specialising in applied statistics and data analysis, with experience in research projects in medicine, biology, ecology and other scientific fields. Able to develop statistical solutions tailored to complex problems and to work effectively within multidisciplinary teams.
Alejandra Martínez Pérez	Ver biodata Pre-doctoral researcher in Tumour Immunology at the University of Oviedo, specialising in cancer immunotherapy. She has experience in biomedical research, particularly in flow cytometry, cell culture, immunophenotyping, functional assays and molecular analysis. Her research focuses on the study of new immunological targets in chronic lymphocytic leukaemia. She combines her research work with university teaching in the field of Immunology.
Rubén Linares Hernández	Ver biodata Pre-doctoral researcher in Tumour Immunology at the University of Oviedo, specialising in cancer immunotherapy. She has experience in biomedical research, particularly in flow cytometry, cell culture, immunophenotyping, functional assays and molecular analysis. Her research focuses on the study of new immunological targets in chronic lymphocytic leukaemia. She combines her research work with university teaching in the field of Immunology.

Objectives

To provide students with the fundamental concepts and techniques of biostatistics and basic epidemiology necessary to design simple studies, analyse biomedical data using computer software and correctly interpret their results, within the framework of evidence-based medicine.

Prerequisites

Recommended: secondary school level knowledge of mathematics.

Competencies

RC13. Be able to design and carry out simple statistical studies using computer software and interpret the results.

RC14. To understand and critically interpret scientific texts.

RC15. Understand and apply the principles of (best) evidence-based medicine.

Learning outcomes

RK39. To be familiar with the basic concepts of biostatistics and their application to the medical sciences.

RS8. Understand and interpret statistical data in the medical literature.

RS9. Use a personal computer independently.

RS12. Present scientific work and/or professional reports in public, both orally and in writing.

Course description

A core module covering compulsory core content on statistical methods, applied statistics, basic epidemiology and evidence-based medicine. Students must acquire skills in introductory research, including information sources, new technologies and databases.

KNOW:

1. Understand the basic concepts of biostatistics and their applicability to the biomedical sciences.

2. Design and analyse simple studies.

3. Understand the main statistical techniques and their application.

4. Understand the usefulness and applications of statistical software.

5. Distinguish between a sample and a population, as well as between random and non-random samples.

6. To analyse a dataset descriptively.

7. Understand the most important distributions and know when to use them.

8. Construct and interpret confidence intervals for means and proportions.

9. Formulate the hypotheses for a hypothesis test based on the aim of the experiment, and understand their limitations and interpretation.

10. Understand the relationship between confidence intervals and hypothesis testing.

11. Interpret the p-value and draw conclusions.

12. Distinguish between independent and paired samples.

13. Distinguish between parametric and non-parametric methods.

14. Test one or two means or proportions depending on the type and number of data points.

15. Understand the applications of the chi-squared test, recognise the limitations of the technique and analyse the reasons for its significance.

16. Understand the concepts of risk factor, relative risk, odds ratio and aetiological fraction.

17. The problem of multiple comparisons and the Bonferroni correction.

18. Understand the concept and interpretation of simple linear regression and correlation studies.

19. Understand the concept and interpretation of survival analysis. The Kaplan–Meier method.

20. Understand the concept, purpose and design of a clinical trial. Meta-analysis.

21. Evidence-based medicine.

SKILLS:

1. Interpret the levels of precision, confidence and error in the conclusions of a statistical study.

2. Use a statistical software package at a user level.

3. Analyse data descriptively.

4. Calculate confidence intervals for means and proportions, determining the appropriate sample size.

5. Formulate the hypotheses for a hypothesis test.

6. Calculate the p-value.

7. Compare two means.

8. Compare two proportions.

9. Analyse a contingency table using the chi-squared test.

10. Apply the Bonferroni method.

11. Plot a scatter plot, regression line and correlation coefficient for two variables.

12. Calculate Spearman’s correlation coefficient.

13. Create a database.

14. Use a personal computer and the most commonly used medical software independently.

To have practised the following under the supervision of a tutor:

1. Break down contingency tables to identify the reasons for the significance of a chi-squared test.

2. Transform variables to ensure they meet the specifications of the model to be used.

3. Obtain confidence intervals for normality in linear regression.

4. Calculate the appropriate measure in an epidemiological study.

5. Evaluate a binary diagnostic method. Perform exact tests for two proportions.

6. Compare several means using parametric and non-parametric methods.

7. Perform multiple regression.

8. Use a personal computer independently and operate the most commonly used medical software.

Contents:

BLOCK I. INTRODUCTION AND DESCRIPTIVE STATISTICS

˗ UNIT 1: The scientific and statistical method. Clinical trials and meta-analyses.

˗ UNIT 2: Population and sample. Characteristics. Classification and description of traits. Types of variables.

˗ UNIT 3: Questionnaires: variables and measurement scales. Clinical measurement.

˗ UNIT 4: Qualitative variables: frequency distributions and graphical representation.

˗ UNIT 5: Quantitative variables: measures of central tendency, position, dispersion and shape. Graphical representation.

BLOCK II. PROBABILITY

˗ UNIT 6: Probability and the assignment of probabilities.

˗ UNIT 7: Conditional probability. Bayes’ theorem. Clinical diagnosis. Sensitivity, specificity and ROC curves.

BLOCK III. PROBABILITY DISTRIBUTIONS

˗ UNIT 8: Random variables: probability function, density and distribution.

˗ UNIT 9: Notable discrete distributions: Binomial and Poisson.

˗ UNIT 10: Notable continuous distributions: the normal distribution and its applications. Approximation between distributions.

BLOCK IV. ESTIMATION AND CONFIDENCE INTERVALS.

˗ UNIT 11: General outline of statistical inference: sampling, bias and the Central Limit Theorem. Statistical tests.

˗ UNIT 12: Estimation of a mean: point estimate and confidence interval. Sample size.

˗ UNIT 13: Estimation of a proportion: confidence interval. Sample size.

BLOCK V. HYPOTHESIS TESTING. COMPARISONS AND MODELS.

- UNIT 14: Introduction to hypothesis testing. Testing the mean of a population.

- UNIT 15: Testing the means of two populations.

- UNIT 16: Comparison of two means: independent and paired samples. Parametric and non-parametric tests.

- UNIT 17: Comparison of two proportions. Contingency tables: chi-squared test. Bonferroni correction and statistical power.

˗ UNIT 18: Linear regression, correlation and ANOVA.

- UNIT 19: Evidence-Based Medicine.

Training activities

1. Lectures: Explanation of the theoretical foundations of statistical methods, applied statistics and basic epidemiology, using computer tools and audiovisual resources. 45 hours (45 face-to-face).

2. Specialised seminars: Solving exercises and applied problems based on the content covered in the lectures, with active student participation and joint discussion of the results. Presentation, study and discussion of case studies or projects. Presentation of projects. Discussion of popular science articles. 10 hours (10 face-to-face).

3. Laboratory sessions: Use of statistical software for the descriptive and inferential analysis of data sets, under the supervision of teaching staff. 10 hours (10 face-to-face).

4. Individual tutorials: Personalised sessions, by appointment, to address queries and monitor the student’s learning progress. 1 hour (1 face-to-face session).

5. Exams: Assessments of theoretical content and laboratory practicals. 4 hours (4 face-to-face).

6. Independent study: Study of theoretical and practical content, completion of additional exercises and consultation of the recommended reading list. 105 hours (0 face-to-face).

Total: 175 hours (70 face-to-face).

Assessment system and criteria

SE1: Objective assessment by teaching staff via the final course examination and a mid-term examination: 70%

SE2: Assessment of the student’s attendance and participation in class: 5%

SE3: Assessment of laboratory practicals via an examination or submission of practical work: 15%

SE4: Assessment of individual and/or group assignments through submission and/or presentation of work: 10%

Timetable

Click on this link to view the detailed timetable in Excel

Session	Activity	Description	Assessment
1	MG	Course introduction
2	MG	UNIT 1: Scientific and statistical methods. Clinical trials and meta-analyses.
3	MG	UNIT 2: Population and sample. Characteristics. Classification and description of traits. Types of variables.
4	MG	UNIT 2: Population and sample. Characteristics. Classification and description of traits. Types of variables.
5	MG	UNIT 3: Questionnaires: variables and measurement scales. Measurement in clinical practice.
6	MG	UNIT 3: Questionnaires: variables and measurement scales. Clinical measurement.
7	MG	UNIT 4: Qualitative variables: frequency distributions and graphical representation.
8	MG	UNIT 4: Qualitative variables: frequency distribution and graphical representation.
9	MG	Revision
10	MG	UNIT 5: Quantitative variables: measures of central tendency, position, dispersion and shape. Graphical representation.
11	MG	UNIT 5: Quantitative variables: measures of central tendency, position, dispersion and shape. Graphical representation.
12	SM	Exercises I: Solving descriptive statistics exercises.
13	MG	UNIT 6: Probability and probability distribution.
14	MG	UNIT 6: Probability and probability distribution.
15	MG	UNIT 7: Conditional probability. Bayes’ theorem. Clinical diagnosis. Sensitivity, specificity and ROC curves.
16	MG	UNIT 7: Conditional probability. Bayes’ theorem. Clinical diagnosis. Sensitivity, specificity and ROC curves.
17	MG	UNIT 8: Random variables: probability function, density and distribution.
18	SM	Exercises II: Solving descriptive statistics exercises
19	MG	UNIT 9: Notable discrete distributions: Binomial and Poisson.
20	MG	UNIT 9: Notable discrete distributions: Binomial and Poisson.
21	MG	UNIT 8: Random variables: probability function, density and distribution.
22	MG	UNIT 10: Notable continuous distributions: the normal distribution and its applications. Approximation between distributions.
23	SM	Exercises III: Solving probability problems
24	MG	Mid-term exam (covering content up to Unit 6)
25	MG	UNIT 10: Notable continuous distributions: the normal distribution and its applications. Approximation between distributions.
26	MG	UNIT 11: General outline of inference: sampling, bias and the Central Limit Theorem.
27	MG	UNIT 11: General framework of inference: sampling, bias and the Central Limit Theorem.
28	MG	UNIT 13: Estimating a proportion: confidence interval. Sample size.
29	MG	UNIT 12: Estimating a mean: point estimate and confidence interval. Sample size.
30	SM	Exercises IV: Solving exercises on probability distributions
31	MG	UNIT 13: Estimating a proportion: confidence interval. Sample size.
32	MG	UNIT 14: Introduction to hypothesis testing. Testing the mean of a population.
33	MG	UNIT 14: Introduction to hypothesis testing. Testing the mean of a population.
34	MG	UNIT 12: Estimating a mean: point estimate and confidence interval. Sample size
35	MG	UNIT 14: Introduction to hypothesis testing. Testing the mean of a population.
36	SM	Exercises V: Solving exercises on probability distributions
37	MG	UNIT 15: Comparing the means of two populations
38	MG	UNIT 15: Comparing the means of two populations
39	MG	UNIT 19: Evidence-Based Medicine
40	MG	UNIT 16: Comparison of two means: independent and paired samples. Parametric and non-parametric tests.
41	MG	UNIT 16: Comparison of two means: independent and paired samples. Parametric and non-parametric tests.
42	SM	Exercises VI: Solving exercises on probability distributions
43	MG	UNIT 16: Comparing two means: independent and paired samples. Parametric and non-parametric tests.
44	SM	Exercises VII: Solving hypothesis testing exercises
45	LB	Descriptive statistics and conditional probability. Contingency tables.
46	LB	Confidence intervals and sample sizes.
47	LB	Association of qualitative variables: hypothesis testing and quantitative variables.
48	MG	UNIT 17: Comparison of two proportions. Contingency tables: chi-squared test. Bonferroni correction.
49	LB	Association between quantitative variables. Assessment of practicals (submission of practicals)	15
50	MG	UNIT 17: Comparison of two proportions. Contingency tables: chi-squared test. Bonferroni correction.
51	MG	UNIT 17: Comparison of two proportions. Contingency tables: chi-squared test. Bonferroni correction.
52	MG	UNIT 18: Linear regression, correlation and ANOVA.
53	MG	UNIT 18: Linear regression, correlation and ANOVA.
54	MG	UNIT 18: Linear regression, correlation and ANOVA.
55	SM	Exercises VIII: Solving hypothesis testing exercises
56	MG	UNIT 18: Linear regression, correlation and ANOVA.
57	MG	Revision
58	SM	Exercises IX: Solving hypothesis testing exercises. Survival analysis.
59	SM	Exercises X: Solving final exercises and addressing queries. Submission and presentation of individual and/or group work	10
60	CN	Tutorial to monitor the learning process (date to be confirmed, at the student’s request). Assessment of attendance and participation	5
61	EV	Final examination for the module (official date as per the examination timetable; not included in the teaching plan)	70

Bibliography

Core:

1. Martínez González, Miguel Ángel, editor; Sánchez-Villegas, Almudena; Toledo Atucha, Estefanía; Faulín Fajardo, Francisco Javier

Biostatistics Made Easy

5th ed. Elsevier. 2025.

ISBN: 9788413829821

http://sapiens.uax.com/discovery/fulldisplay?docid=alma99922055803591&context=L&vid=34UAX_INST:34UAX_V1&lang=es&search_scope=MyInst_and_CI&adaptor=Local%20Search%20Engine&tab=Everything&query=any,contains,biostatistics&sortby=date_d&facet=frbrgroupid,include,9001610310540091269&offset=0

TOTAL:

SECOND FOUR-MONTH TERM

Code

Subjects

Character*

ECTS

N10205

Bioethics

Código: N10205 Imprimir

Course 1: Second-term module. Compulsory. 4 credits.

Profesores

Patricia Leonor Rodríguez Suárez	Ver biodata I defended my doctoral thesis at the University of Oviedo, entitled ‘Physical health in patients with depressive disorders: a naturalistic study’, and was awarded the grade ‘outstanding cum laude’. I subsequently completed a Master’s degree in Bioethics at UCAM and a Master’s degree in Clinical Simulation at FUDEN in Madrid. I have also recently obtained a degree in Theology from the University of Deusto. Although my primary focus is on clinical practice in A&E medicine, I continue to conduct research and actively contribute to my hospital’s healthcare ethics committee, as well as to the training of medical students and junior doctors, primarily in advanced life support, severe trauma care and bioethics.
María Teresa González Martínez	Ver biodata Specialisation: Paediatrics and Specific Areas Master’s degree in Neonatology from the Catholic University of Valencia. Continuing Professional Development diplomas in ‘Health Law and Bioethics’, ‘Bioethics: Trainer of Trainers’, ‘Advanced Bioethics’, ‘Statistics in Health Sciences’ and ‘Medical Genetics’. Teaching: Healthcare technology. Contributor to PhD programmes and numerous accredited conferences and courses, primarily on topics relating to neonatology, breastfeeding and bioethics. Clinical practice as a paediatrician and neonatologist in various hospitals within the Castile and Asturias health services Volunteer work with the United Nations. Training Officer at the Training Service of the Directorate-General for Human Resources of the SACYL. Since 2005, member of Ethics Committees for healthcare. Chair of the Ethics Committee for Healthcare in Area V since 2022. Collaboration in multicentre research groups: Multicentre study by the Spanish Society of Neonatology: SEN-1500. Euroneonet multicentre study. Asturian Register of Congenital Malformations. Asturian Neonatal Mortality Register. Asturian Register of Congenital Defects. Spanish Collaborative Study on Congenital Malformations (ECEMC). Book chapters, articles and conference papers on paediatrics, neonatology and bioethics.
Cristina Magadán Álvarez	Ver biodata Bachelor of Medicine from the University of Cantabria (2007–2013), including an Erasmus placement at Ghent University (Belgium). Completed her MIR training in General and Gastrointestinal Surgery at the Marqués de Valdecilla University Hospital (2014–2019), including a placement as an International Research Fellow at NYU Winthrop Hospital (2017). Senior Registrar (FEA) in General and Gastrointestinal Surgery at San Agustín University Hospital (Avilés) since 2019. PhD from the University of Cantabria (2023), with a thesis on short- and long-term survival in hepatocellular carcinoma treated by resection or liver transplantation. Master’s degree in Breast Surgery from the University of Barcelona (2023). Author and co-author of publications in national and international scientific journals, including Annals of Surgery, British Journal of Surgery and Cirugía Española. Lecturer at San Agustín University Hospital and honorary lecturer at the University of Oviedo since 2019. Master’s degree in Teaching from Alfonso X el Sabio University (2026). Undergraduate Programme Coordinator in Medicine at the Alfonso X Asturias University Centre.
Alejandra Martínez Pérez - Coordinador	Ver biodata Pre-doctoral researcher in Tumour Immunology at the University of Oviedo, specialising in cancer immunotherapy. She has experience in biomedical research, particularly in flow cytometry, cell culture, immunophenotyping, functional assays and molecular analysis. Her research focuses on the study of new immunological targets in chronic lymphocytic leukaemia. She combines her research work with university teaching in the field of Immunology.

N10206

Genetics

Código: N10206 Imprimir

Course 1. Second-term module. Foundation course. 6 credits.

Profesores

Maria Dolores Chiara Romero	Ver biodata A doctor of medicine and holder of a PhD from the University of Seville, with postdoctoral training at Harvard Medical School, where he contributed to elucidating the mechanisms of pre-mRNA splicing and to identifying components of the spliceosome. On his return to Spain, he investigated the diversity of ion channels and, as a Miguel Servet Research Fellow at the Virgen del Rocío Hospital, identified HIF as a regulator of ion channel genes and characterised T-type calcium channels in hypoxia-induced excitability. Since 2002, he has been a Full Professor at the University of Seville (currently on voluntary leave of absence) and, subsequently, a Miguel Servet Research Fellow at the Central Hospital of Asturias (Oviedo), where he leads the Rare Tumours Group (Health Research Institute of the Principality of Asturias – ISPA / University Institute of Oncology of the Principality of Asturias – IUOPA). His research focuses on the molecular mechanisms of cancer progression, the tumour microenvironment, and tumours driven by hypoxia and mutations in mitochondrial complex II genes. Key indicators: over 70 publications, H-index = 24, 2,134 citations, 5 recognised six-year research periods, 13 doctoral theses supervised (Cum Laude) and 5 patents.
Alejandra Martínez Pérez	Ver biodata Pre-doctoral researcher in Tumour Immunology at the University of Oviedo, specialising in cancer immunotherapy. She has experience in biomedical research, particularly in flow cytometry, cell culture, immunophenotyping, functional assays and molecular analysis. Her research focuses on the study of new immunological targets in chronic lymphocytic leukaemia. She combines her research work with university teaching in the field of Immunology.
Belén Alonso Estanillo - Coordinador	Ver biodata Bachelor’s degree in Molecular Biology. PhD in Biology and Biochemistry. Her areas of expertise are Biochemistry and Genetics. She has 12 years’ teaching experience, during which she has taught the following subjects: Biochemistry, Genetics, Physiology and Biology. She has 17 years’ professional experience. Her professional experience includes: research into the biology of cetaceans and primates. Lecturer at a university college and a university. Veterinary laboratory technician (ATV) at a veterinary hospital.
Mario García Domínguez	Ver biodata Bachelor’s degree in Molecular Biology. PhD in Biology and Biochemistry. Her areas of expertise are Biochemistry and Genetics. She has 12 years’ teaching experience, during which she has taught the following subjects: Biochemistry, Genetics, Physiology and Biology. She has 17 years’ professional experience. Her professional experience includes: research into the biology of cetaceans and primates. Lecturer at a university college and a university. Veterinary laboratory technician (ATV) at a veterinary hospital.
Paula Díaz Bulnes	Ver biodata Bachelor’s degree in Molecular Biology. PhD in Biology and Biochemistry. Her areas of expertise are Biochemistry and Genetics. She has 12 years’ teaching experience, during which she has taught the following subjects: Biochemistry, Genetics, Physiology and Biology. She has 17 years’ professional experience. Her professional experience includes: research into the biology of cetaceans and primates. Lecturer at a university college and a university. Veterinary laboratory technician (ATV) at a veterinary hospital.

N10207

Immunology

Código: N10207 Imprimir

Course 1. Second-term module. Foundation course. 6 credits.

Profesores

Alejandra Martínez Pérez	Ver biodata Pre-doctoral researcher in Tumour Immunology at the University of Oviedo, specialising in cancer immunotherapy. She has experience in biomedical research, particularly in flow cytometry, cell culture, immunophenotyping, functional assays and molecular analysis. Her research focuses on the study of new immunological targets in chronic lymphocytic leukaemia. She combines her research work with university teaching in the field of Immunology.
Belén Alonso Estanillo	Ver biodata Bachelor’s degree in molecular biology. PhD in biology and biochemistry. Her areas of expertise are biochemistry and genetics. She has 12 years’ teaching experience, during which she has taught the following subjects: biochemistry, genetics, physiology and biology. She has 17 years’ professional experience. Her professional experience includes: research into the biology of cetaceans and primates. Lecturer at a university college and a university. Veterinary laboratory technician (ATV) at a veterinary hospital.
Sarah Panera Martínez	Ver biodata I hold a degree in Biology from the University of León, a Master’s degree in Plant Biotechnology (University of Oviedo), a Master’s degree in Biostatistics and Bioinformatics (Open University of Catalonia), in Teacher Training (International University of La Rioja) and hold a PhD in Veterinary and Food Sciences from the University of León. I hold accreditation as an Assistant Lecturer from the ACSUCY, having accumulated more than 450 hours of teaching experience at the University of León and the International University of La Rioja.
David Carballo Beltrán - Coordinador	Ver biodata I hold a degree in Biology from the University of León, a Master’s degree in Plant Biotechnology (University of Oviedo), a Master’s degree in Biostatistics and Bioinformatics (Open University of Catalonia), in Teacher Training (International University of La Rioja) and hold a PhD in Veterinary and Food Sciences from the University of León. I hold accreditation as an Assistant Lecturer from the ACSUCY, having accumulated more than 450 hours of teaching experience at the University of León and the International University of La Rioja.
Mario García Domínguez	Ver biodata I hold a degree in Biology from the University of León, a Master’s degree in Plant Biotechnology (University of Oviedo), a Master’s degree in Biostatistics and Bioinformatics (Open University of Catalonia), in Teacher Training (International University of La Rioja) and hold a PhD in Veterinary and Food Sciences from the University of León. I hold accreditation as an Assistant Lecturer from the ACSUCY, having accumulated more than 450 hours of teaching experience at the University of León and the International University of La Rioja.
Paula Díaz Bulnes	Ver biodata I hold a degree in Biology from the University of León, a Master’s degree in Plant Biotechnology (University of Oviedo), a Master’s degree in Biostatistics and Bioinformatics (Open University of Catalonia), in Teacher Training (International University of La Rioja) and hold a PhD in Veterinary and Food Sciences from the University of León. I hold accreditation as an Assistant Lecturer from the ACSUCY, having accumulated more than 450 hours of teaching experience at the University of León and the International University of La Rioja.

N10208

History of Medicine

Código: N10208 Imprimir

Course 1: Second-term module. Compulsory. 4 credits.

Profesores

Fernando Floriano Fernández - Coordinador	Ver biodata Bachelor of Medicine and Surgery and Graduate in History. PhD candidate in Humanities Research, specialising in the digital editing of historical documents at the University of Oviedo. General practitioner, specialising in Admissions and Clinical Documentation. A doctor with over 35 years’ experience in healthcare management, hospital administration and clinical documentation. University-qualified specialist in healthcare services management with advanced training in coding (ICD-9-CM and ICD-10-ES), DRG systems and the analysis of hospital indicators. Tutor to MIR residents in Preventive Medicine and Public Health and Coordinator of work placements for vocational training students studying for the ‘Higher Technician in Healthcare Documentation and Administration’ qualification at the Central University Hospital of Asturias. Experience in clinical services management, the implementation of healthcare information systems, the training and development of professional teams, and research into documentation and historical analysis.
Jaime de Algorta de Pineda	Ver biodata Doctor of Medicine (1993, New stimuli for growth hormone secretion. Supervisor: Prof. Dr Pedro Martul Tobio), accredited by ANECA and UNIQAL, certified EuCP pharmacologist, with 30 years’ professional experience divided between clinical medicine (Col. 334806789) and clinical research across all its fields: as principal investigator of clinical trials in hospitals, as a sponsor within the pharmaceutical industry, and as a clinical development consultant for research firms and scientific and regulatory consultancy firms. All of the above has been combined with academic and teaching activities at various universities and educational institutions.
Julio César Pérez Herrero	Ver biodata PhD in Information Sciences. Accredited lecturer in all teaching roles by ANECA and the Madrid+d Foundation. Qualified as a full professor in Social Sciences. Two six-year research terms completed and currently in my third. Author and/or editor of eight books, and more than twenty academic articles in indexed journals. Political analyst for various national media outlets.

Objectives

1. To understand the development of the key scientific events and knowledge relating to the historical development of medicine.

2. To understand the evolution of the concepts of health, illness and the medical profession throughout history.

3. To understand human attitudes towards health, illness and death throughout history.

4. To learn how to consult and analyse historical sources in medicine.

5. To engage in independent study using existing documentary sources.

Prerequisites

Basic secondary school knowledge.

KNOW

Recognise, diagnose and guide its management

1. Reflect on the biological, historical, social and cultural nature of the

concepts of health and illness.

2. Analyse the responses of human communities to the problem of

illness (medical systems) and situate, within the framework of these responses,

modern medicine. Ethnomedicine and alternative medicines.

3. Describe the scientific method from a historical perspective, specifying

the various approaches that have been and are currently used to gain

scientific understanding of reality.

4. Identify and interpret the circumstances that have influenced the development of

medicine as a profession.

5. Develop an information culture within the medical profession so that

professionals can make better use of the available resources with

judgement.

6. Explain the concepts of demographic, health and epidemiological transition

in Western European populations.

7. Analyse the process by which knowledge is constructed concerning the human being

in states of health and illness.

8. Explain the fundamental pathways in the development of therapeutics in

its various forms.

9. Explain the process of transition from personal hygiene to public health

and community health.

10. Understand the historical development of health services, their organisation and

the different models of healthcare provision.

11. Recognise the existence and reasons for the emergence of different

, distinguish the relationships between them and define the mechanisms of

professionalisation.

12. To understand the issues associated with the practice of medicine and to relate

them to the institutions that have regulated it and their ethical and

deontological approaches.

13. To understand the significance and the main contributions of the various

schools and figures of Greco-Roman Classical Antiquity.

14. Highlight the importance, in medieval Europe, of the process of transmitting

of classical knowledge in a multicultural society.

15. Explain the most significant characteristics of European medicine from

the Renaissance period to contemporary industrialised societies.

16. Identify the key figures in contemporary Spanish medicine

(Cajal, Ochoa, etc.) as representative examples of approaches to the

in medicine.

PRACTICAL SKILLS

Be able to perform competently (routinely and without supervision).

To have practised this under supervision (under the supervision of a tutor)

1. Recognise the elements that provide cohesion and shape the current identity

of the medical profession as the result of a historical process.

2. Identify the various constituent elements of medical knowledge and

medical practice in order to gain an overview of them and of the role

they play in a doctor’s training.

3. Give examples of how the concept of disease has evolved

over time, in response to scientific and sociocultural factors.

4. Identify, in the light of history, ways of understanding the values and

attitudes of respect towards the sick person.

KNOWLEDGE

RK40 – Understand the history of health and illness.

RK41 – Understand the existence and principles of alternative medicines.

RK42 – Understand the principles of the scientific method, biomedical research and clinical trials.

SKILLS AND ABILITIES

RS10 – Use systems for searching for and retrieving biomedical information.

RS12 – Present scientific work and/or professional reports in public, both orally and in writing.

COMPETENCIES

RODS – To develop effective communication, teamwork, analytical thinking, creativity and ethical leadership

from a cross-disciplinary perspective and clearly inspired by democratic principles and values, as well as the Sustainable Development Goals

Sustainable Development, in order to conduct oneself with integrity in the professional sphere.

Course description

Historical evolution of medicine from its beginnings to the present day. Key figures, their theories and technical achievements. Changes in the understanding of disease and theories regarding its causes.

LECTURES

Unit 1. The biological and cultural evolution of disease.

1. The biological and cultural evolution of disease.

2. Major epidemics in history.

3. Chronic infectious diseases.

Unit 2. Pre-scientific medicine

4. Pre-scientific medical practices

5. Medicine in the great civilisations.

Unit 3. Classical Medicine.

6. Hippocrates and the birth of Classical Medicine.

7. Hellenistic Medicine.

8. Medicine in Rome.

Unit 4. Medieval Medicine

9. The Middle Ages in the East.

10. The Middle Ages in the West.

Unit 5. Medicine in the Renaissance and the Enlightenment.

11. Medicine in the Renaissance (16th century).

12. Medicine during the Scientific Revolution (17th century).

13. Medicine during the Enlightenment (18th century).

Unit 6. Contemporary Medicine.

14. Medicine in the 19th Century.

15. Medicine in the 20th Century.

16. Medicine in the 21st Century.

Unit 7. Medicine, Science and Scientific Language.

17. History of the Scientific Method.

18. Scientific Language.

INTERACTIVE SEMINARS:

Participation and presentation of papers based on the content of the lectures and on specific topics from the reading list.

TRAINING ACTIVITIES

1. Lecture (traditional methodology): Explanation of theoretical principles, using IT tools.

2. Case study method

3. Problem-based learning

4. Experiential learning

5. Workshop-based learning and practical skills

6. Service-learning

7. Collaborative learning

TOTAL:

Second Year

ANNUAL SUBJECTS

Code	Subjects	Character*	ECTS
N20200	Morphology, Structure and Function of Organs and Systems III	FB	16

N20201	Morphology, Structure and Function of Organs and Systems IV	FB	10

N20202	Microbiology	FB	10

TOTAL:			36

FIRST FOUR-MONTH TERM

Code	Subjects	Character*	ECTS
N20203	Biochemistry II	FB	6

TOTAL:			6

SECOND FOUR-MONTH PERIOD

Code	Subjects	Character*	ECTS
N20204	Biophysics and Basic Radiology	OB	6

N20205	Medical Psychology	OB	6

TOTAL:			12

OPTIONAL SUBJECTS

Code	Subjects	Character*	ECTS
N/A	Elective	OP	6

TOTAL:			6

Third Year

ANNUAL SUBJECTS

Code	Subjects	Character*	ECTS
N30200	Pathological Anatomy	OB	12

N30201	Pharmacology	OB	9

N30202	General Medical and Surgical Procedures	OB	18

TOTAL:			39

FIRST FOUR-MONTH PERIOD

Code	Subjects	Character*	ECTS
N30203	The legal foundations of medicine	OB	5

N30204	Epidemiology	OB	4

TOTAL:			9

SECOND FOUR-MONTH TERM

Code	Subjects	Character*	ECTS
N30205	Digital health	OB	5

N30206	Physical Medicine and Rehabilitation	OB	3

N30207	Preventive Medicine and Public Health	OB	4

TOTAL:			12

Year 4

ANNUAL SUBJECTS

Code	Subjects	Character*	ECTS
N40200	Practical Clinic I	OB	6

N40201	Obstetrics and Gynaecology	OB	10

N40202	Cardiovascular Medical and Surgical Pathology	OB	7

N40203	Medical and Surgical Pathology Pulmonary Medicine	OB	6

N40204	Medical and surgical neurological pathology	OB	7

N40205	Dermatology	OB	5

N40206	Infectious diseases	OB	7

TOTAL:			48

SECOND FOUR-MONTH TERM

Code	Subjects	Character*	ECTS
N40207	Ophthalmology	OB	6

N40208	Ear, Nose and Throat Medicine	OB	6

TOTAL:			12

Year 5

ANNUAL SUBJECTS

Code	Subjects	Character*	ECTS
N50200	Practical Clinic II	OB	12

N50201	Paediatrics	OB	10

N50202	Medical and Surgical Pathology of the Digestive System	OB	6

N50203	Rheumatology and Orthopaedics	OB	6

N50204	Medical and Surgical Pathology Endocrinology and Nutrition	OB	7

N50205	Medical and Surgical Pathology Uro-nephrological	OB	7

N50206	Psychiatry	OB	6

N50207	Onco-haematology and clinical genetics	OB	6

TOTAL:			60

Year 6

ANNUAL SUBJECTS

Code	Subjects	Character*	ECTS
N60200	Clinical Practice III	OB	36

N60203	Final Year Project	OB	6

TOTAL:			42

FIRST FOUR-MONTH PERIOD

Code	Subjects	Character*	ECTS
N60201	Clinical pharmacology and toxicology	OB	7

N60202	Primary care and geriatrics	OB	5

TOTAL:			12

OPTIONAL SUBJECTS

Code	Subjects	Character*	ECTS
N/A	Elective	OP	6

TOTAL:			6

List of Optional Modules

FIRST FOUR-MONTH PERIOD

Code	Subjects	Character*	ECTS
N20230	Precision medicine	OP	6

N20231	English	OP	6

N20232	Interpersonal Communication in the Digital Age and Leadership	OP	6

N60230	Urgent and emergency cases	OP	6

N60231	Critics	OP	6

N60232	Health Management and Economics	OP	6

TOTAL:			36

*Character: BT: Basic Training, Ob: Required, Op: Optional

UAX Asturias: The new technological hub for healthcare in Oviedo.

Campus Oviedo

CAMPUS

OVIEDO

ASTURIAS

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The images shown are digital renderings of the UAX Asturias campus and may be subject to change.

Classrooms

Laboratories

Café

Assembly hall

Communal areas

Access and admission

The Bachelor’s Degree in Medicine is aimed at students who have completed their Baccalaureate, Vocational Training or equivalent qualifications, who have passed the University Entrance Examinations (PAU) and who are interested in developing their careers as doctors.

SPECIFIC ENTRANCE EXAMINATION FOR THE BACHELOR’S DEGREE IN MEDICINE

It consists of two parts:

Part One: Multiple-choice examination in Biology (30 questions) and Chemistry (20 questions).
Part Two: Personal interview

Start admission process

Grants and financial aid to study medicine

At UAX we know that studying is an investment, that's why we provide you with the facilities you need to access our degrees. Find out about some of our scholarships and grants:

Grants from official bodies: Community of Madrid and Ministry of Education.
Study aid for UAX excellence
Study grants for family members of UAX students
Study grants for continuity of studies UAX
Study grants for elite sportsmen and women UAX
UAX financing plans

Request information

Career opportunities in Medicine

According to the latest study published by the Ivie and the BBVA Foundation, the degree in Medicine has the highest job placement rate.

Public and private healthcare system.
Assistance in: treatment, diagnosis, prevention, promotion and restoration of health in hospitals and health centres, among others.
Development of teaching activities in the training of health professionals.
Biomedical research, both basic and applied.
Pharmaceutical and biotechnological industry.
Management, administration and management of health centres.

The UAX Degree in Medicine has access to a regulated profession.

Order ECI/332/2008, of 13 February, BOE of 15 February 2008.

Not sure?
We can help you find the programme that best suits your profile.

Contact UAX

María Victoria Ruiz

Grado en Medicina

He elegido estudiar Medicina en UAX por su experiencia formando médicos, por las instalaciones y por el prestigio de las prácticas, ya que las rotaciones se realizan por muchas especialidades y sales muy bien preparado.